One of the most fundamental assumptions in biology is that the amino acid sequence defines protein structure and that this sequence carries no memory of the specific mRNA codon sequence from which it was translated.

Mitochondrial diseases (MDs) are the largest and most common group of inherited metabolic disorders. They comprise over 350 monogenic diseases and affect at least one child born each week in Australia.

Nutritional deficiencies are a leading cause of human susceptibility to infectious diseases and antibiotic treatment failure. Specifically, our intake of dietary lipids has changed dramatically, yet microbe-lipid interactions during infection are poorly understood.

Bacterial infections remain a global public health challenge and there is a critical need for the identification and molecular understanding of new targets for antimicrobial design.

Current treatments for malaria are threatened by drug resistance, and new antimalarials are urgently required to ensure the continued ability to treat malaria infections into the future.

B0AT1 (Slc6a19) is a sodium-dependent neutral amino acid transporter catalyzing the secondary active transport of neutral amino acids across the brush border membrane of the kidney and intestine.