News & events

Bacterial flagella self-assemble a strong, multi-component drive shaft that couples rotation in the inner membrane to the microns-long flagellar filament that powers bacterial swimming in viscous fluids.

The antimalarial drug amodiaquine has been around for nearly 60 years during which time it has been deployed as a monotherapy, then removed from recommendations due to toxicity fears, re-instated, and is now deployed in artemisinin-based combinations therapies to combat malaria.

As you read this abstract, your lungs are (I hope!) bringing live-sustaining oxygen into your body. Oxygen is required by our cells for one key purpose – to act as the final electron acceptor in the mitochondrial electron transport chain (ETC).

Shigella flexneri is an entero-pathogen that is considered a significant public health risk, causing shigellosis or bacillary dysentery, and accounts for the highest percentage of diarrheal deaths annually.

Scientific and technological advancements in the field of cell physiology over the last thirty years have uncovered the identities and functions of over sixty solute carriers which participate in the transport of amino acids in mammalian cells.

Many genes that have been recently identified as determinants of drug resistance in the malaria parasite encode membrane transport proteins (also known as transporters).