Projects

Project	Research theme	Group
A chytrid fungus nanobody toolkit and genetic transformation approaches	Infection and immunity Host-microbe biology	Tham Group - Understanding chytrid infection biology
A yeast surface display nanobody factory	Infection and immunity	Brock Group - Membrane Structural & Synthetic Biology
Biologically inspired membranes for the efficient desalination of water	Membrane transporters and channels Bioinformatics and bio-mathematical modelling	Corry Group - Transport proteins and computational biophysics
Caenorhabditis elegans as a potential animal model to study host-pathogen interactions	Infection and immunity Host-microbe biology	Verma Group - Bacterial and bacteriophage genetics, and vaccine development
Cellular adaptations that allow the transmission and survival of Plasmodium falciparum when taken up by the mosquito	Host-microbe biology Membrane transporters and channels Parasitology	Maier Group - Molecular mechanisms of malaria pathogenesis
Chromosome condensation and T cell development	Infection and immunity	Fahrer Group - Immunology
Computational models of nerve conduction	Membrane transporters and channels Bioinformatics and bio-mathematical modelling	Corry Group - Transport proteins and computational biophysics
Coral regeneration	Phylogenetics, population genetics and biodiversity Bioinformatics and bio-mathematical modelling Behavioural, evolutionary and physiological ecology	Adamska Group - Genomic and evolutionary basis of animal development
Designing new channel inhibitors for treating chronic pain	Membrane transporters and channels Bioinformatics and bio-mathematical modelling	Corry Group - Transport proteins and computational biophysics
Development of a simple, inexpensive therapeutic cancer vaccine	Infection and immunity	Fahrer Group - Immunology
Diseases of amino acid transport	Membrane transporters and channels	Broer Group - Membrane transport and nutrition
Engineering the secretory pathways of yeast		Brock Group - Membrane Structural & Synthetic Biology
Erythrocyte membrane modifications during malaria infection	Host-microbe biology Membrane transporters and channels Parasitology	Maier Group - Molecular mechanisms of malaria pathogenesis
Function of molecular chaperones in the export and display of parasite proteins	Host-microbe biology Parasitology	Maier Group - Molecular mechanisms of malaria pathogenesis
Functional characterisation of novel autotransporter proteins	Membrane transporters and channels Infection and immunity	Leyton Group - Assembly, function, and applications of nanoscale bacterial surface structures
How do biological molecules distinguish between ions?	Membrane transporters and channels Bioinformatics and bio-mathematical modelling	Corry Group - Transport proteins and computational biophysics
Identification of 2000 novel protein isoforms in the human and mouse genomes	Evolutionary genetics and genomics Bioinformatics and bio-mathematical modelling	Fahrer Group - Immunology
Identification of molecular mechanisms of action and direct target genes of developmental signalling pathways in sponges	Evolutionary genetics and genomics Bioinformatics and bio-mathematical modelling Behavioural, evolutionary and physiological ecology	Adamska Group - Genomic and evolutionary basis of animal development
Identification of target genes of developmental transcription factors Brachyury, Gata and Caudal in sponges	Evolutionary genetics and genomics Bioinformatics and bio-mathematical modelling Behavioural, evolutionary and physiological ecology	Adamska Group - Genomic and evolutionary basis of animal development
Lipid Regulation of Ion Channels	Membrane transporters and channels Infection and immunity	Corry Group - Transport proteins and computational biophysics
Molecular mechanisms of innate immunity	Membrane transporters and channels Infection and immunity	Corry Group - Transport proteins and computational biophysics
Molecular tools to reveal protein function and identify drug targets	Host-microbe biology Parasitology	Maier Group - Molecular mechanisms of malaria pathogenesis
New molecular targets for drugs to treat human and animal nematode parasites	Host-microbe biology Parasitology	Behm Group - Nematode molecular biology
Novel nutrient/metabolite transporters in apicomplexan parasites	Photosynthesis and plant energy biology Parasitology Membrane transporters and channels Host-microbe biology	van Dooren Group - Cell biology and metabolism of apicomplexan parasites Kirk Group - Membrane transport in parasites
Nutrient acquisition in apicomplexan parasites	Parasitology Membrane transporters and channels Evolutionary genetics and genomics Host-microbe biology	Lehane Group - Antimalarial drug action and resistance van Dooren Group - Cell biology and metabolism of apicomplexan parasites
Olfactory pattern recognition in nematodes	Membrane transporters and channels	Behm Group - Nematode molecular biology
Plasmodium falciparum lipid metabolism as a target for malaria intervention strategies	Membrane transporters and channels Parasitology	Maier Group - Molecular mechanisms of malaria pathogenesis
Redesign and engineering of the autotransporter β-barrel domain	Membrane transporters and channels Infection and immunity	Leyton Group - Assembly, function, and applications of nanoscale bacterial surface structures
Serotype-converting bacteriophages and O-antigen modification in Shigella flexneri	Infection and immunity Host-microbe biology	Verma Group - Bacterial and bacteriophage genetics, and vaccine development
Shigella virulence and vaccine development	Infection and immunity Host-microbe biology	Verma Group - Bacterial and bacteriophage genetics, and vaccine development
Skeleton formation in soft corals and calcareous sponges	Evolutionary genetics and genomics Behavioural, evolutionary and physiological ecology	Adamska Group - Genomic and evolutionary basis of animal development
Sponge and coral microbiomes	Behavioural, evolutionary and physiological ecology Bioinformatics and bio-mathematical modelling Evolutionary genetics and genomics	Adamska Group - Genomic and evolutionary basis of animal development
Structural basis of drug resistance in the Malaria parasite	Parasitology Membrane transporters and channels Host-microbe biology	Brock Group - Membrane Structural & Synthetic Biology
Structural basis of Endometriosis	Membrane transporters and channels	Brock Group - Membrane Structural & Synthetic Biology
Structural basis of Resolvin mediated GPCR signalling		Brock Group - Membrane Structural & Synthetic Biology
Student research projects in tumour immunology and liposome targeting	Infection and immunity	Altin Group - Tumour immunology and liposome targeting group
SynBio enabled biosensors	Membrane transporters and channels Bioinformatics and bio-mathematical modelling Host-microbe biology	Brock Group - Membrane Structural & Synthetic Biology
Targeting ion transport in apicomplexan parasites with new generation antimalarials	Parasitology Membrane transporters and channels Host-microbe biology	Lehane Group - Antimalarial drug action and resistance van Dooren Group - Cell biology and metabolism of apicomplexan parasites
The biology of the mitochondrion of apicomplexan parasites	Parasitology Membrane transporters and channels Evolutionary genetics and genomics Host-microbe biology	van Dooren Group - Cell biology and metabolism of apicomplexan parasites
To what degree does autotransporter folding inside the bacterial cell resemble autotransporter folding in bulk solution?	Membrane transporters and channels Infection and immunity	Leyton Group - Assembly, function, and applications of nanoscale bacterial surface structures
Transport mechanisms and drug resistance in malaria transporters	Parasitology Membrane transporters and channels Infection and immunity Host-microbe biology	Corry Group - Transport proteins and computational biophysics
Understanding how gram-negative bacteria respond to oxidative stress	Membrane transporters and channels Infection and immunity	Furlong Group - Bacterial Structural Defence
Understanding the pathogenesis of the urinary tract pathogen Proteus mirabilis	Membrane transporters and channels Infection and immunity Host-microbe biology	Furlong Group - Bacterial Structural Defence
Understanding the proteins responsible for our sense of touch	Membrane transporters and channels Bioinformatics and bio-mathematical modelling	Corry Group - Transport proteins and computational biophysics
Vitamin utilisation by malaria parasites	Parasitology Membrane transporters and channels Host-microbe biology	Saliba Group - Physiology and biochemistry of the malaria parasite

Updated: 17 October 2023/Responsible Officer: Web Services/Page Contact: Web Services

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