Discover the capabilities of the new Precision Fermentation Facility that has been established at RSB, including an overview of the equipment, its capabilities and potential applications.

Toxic accumulation of phenylalanine underlies the neurological deficits and morbidity in phenylketonuria (PKU). Despite availability of treatment options for PKU patients, high unmet need remains for safe and convenient therapies that work across a broad cross section of PKU patients and allow for diet normalization.

Regeneration is the natural ability to restore or replace damaged or lost body parts following severe injury. Regenerative abilities vary strongly across and within most bilaterian phyla.

DNA stability is a prerequisite in many of its applications, ranging from DNA-based vaccine, data storage to gene therapy. However, the existing strategies to enhance the DNA stability are ineffective and limited in scope.

Synthetic chemistry and synthetic biology offer complementary tools for manipulating the 3D architecture and function of biomolecules. I will outline two different projects that exemplify our hybrid chemical biology approach, highlighting divergent applications in catalysis and cancer therapy.

Associate Professor Kelly Roger's team has built a lattice light sheet microscope which was instrumental in the discovery that mitochondrial DNA is released during apoptosis through BAK and BAX pores in the outer mitochondrial membrane.