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F1Fo ATP synthase generates the majority of cellular energy by interconverting phosphate transfer energy and proton motive force via a rotary catalytic mechanism. Using cryo electron microscopy we have provided molecular snapshots of this complex enzyme in multiple states.

The Acinetobacter genus includes at least 70 named species that occupy environments which differ broadly in nutrient composition, water availability, temperature and other abiotic characteristics.

Malaria remains the deadliest parasitic disease in the world despite years of sustained effort, new drug development, and a greater understanding of the causative parasite, Plasmodium, and its interactions with its host.

Malaria kills around 400,000 people each year and the prevention and treatment of this disease is highly reliant on chemotherapy.

Developing novel synthetic microbes for the sustainable production of biochemical, biofuels and bioplastics is critical for the emergence of a new global bioeconomy.

One of the most fundamental assumptions in biology is that the amino acid sequence defines protein structure and that this sequence carries no memory of the specific mRNA codon sequence from which it was translated.