This presentation highlights high-resolution cryo-EM structures of C. albicans Cdr1 in various substrate-bound states, with and without nucleotides, resolved at 3.45–3.74 Å.

Rubisco is the most abundant protein on earth, catalysing photosynthetic CO2 fixation to provide all usable carbon in the biosphere. However, its slow and non-specific catalytic activity limits crop productivity and its resultant over-production represents a huge nitrogen cost.

Making key insights into antimalarial resistance mechanisms and delineate the utility of cutting-edge computational approaches that will go on to inform future drug design strategies and efforts.

Rust fungi are a diverse group of plant pathogens consisting of over 8,000 species in the Basidiomycete order Pucciniales. They parasitise numerous plants of agricultural and ecological importance, such as cereals, legumes, and trees.

The rust fungi (Pucciniales) comprise the largest order of plant pathogenic fungi and are among the most serious threats to both agricultural crops and natural ecosystems.

Over 50 years ago, the active principle 青蒿素 qīng hāo sū or artemisinin was isolated in pure crystal-line form from the leaves of the Chinese traditional herb 青蒿 qīng hāo - Artemisia annua - by Chinese groups working under the remarkable Project 523 during the latter stages of the Chinese Cultural Revolution.

The Australian agrifood sector faces complex and multifaceted challenges to its continued growth and evolution, including a changing climate and geopolitical instability.

Dr Buchert will present two vignettes highlighting his group’s research in gastric cancer.

This seminar will explore photosynthetic strategies across diverse extreme environments, presenting case studies on cyanobacteria inhabiting marine oxygen deficient zones, algae growing within sea-ice and snow, and chemoautotrophic bacteria encased within ancient anoxic marine brines.