Infection and immunity

Organisms defend themselves against infections through innate and adaptive immune responses. In the Research School of Biology we investigate important pathogens (Shigella, poxviruses and herpesviruses) and how they are recognised by the immune system. We investigate how cells of the immune system develop and how the immune system can be used to fight infectious agents and cancer cells. These approaches are used to generate new vaccines and to develop cancer therapies.

Project Groups
ANU International applicants for PhDs in Biomedical Science and Biochemistry
Caenorhabditis elegans as a potential animal model to study host-pathogen interactions
Chromosome condensation and T cell development
Development of a simple, inexpensive therapeutic cancer vaccine
Functional characterisation of novel autotransporter proteins
Protein function in plant immunity
Redesign and engineering of the autotransporter β-barrel domain
Serotype-converting bacteriophages and O-antigen modification in Shigella flexneri
Shigella virulence and vaccine development
Student research projects in tumour immunology and liposome targeting
To what degree does autotransporter folding inside the bacterial cell resemble autotransporter folding in bulk solution?
Uncovering the hare microbiome