Rust diseases significantly threaten cereals and other crops, causing substantial losses in crop production worldwide and endangering global food security.
Endogenous retroviruses (ERVs), also known as retrotransposons, essentially carry two open reading frames that code for GAG and POL. Some ERVs additionally carry a third gene called envelope (env), becoming infectious.
Phylogenetic distance is a key measure used to develop host test lists that will delimit the fundamental and realised host range of candidate biocontrol agents.
Our group is broadly interested in understanding how metazoan cells fold complex proteins, and how the need to fold those proteins impacts their ability to evolve.