We are investigating diverse epigenetic mechanisms in the context of behaviour and developmental plasticity, mainly using the honey bee model, but we also have close interactions with groups working on other interesting systems.
Honorary Group Leader
Hurd, P.J. Grübel, K. Wojciechowski, M. Maleszka, R. Rössler, W. (2021) Novel structure in the nuclei of honey bee brain neurons revealed by immunostaining. Scientific Reports 11 (1), 1-10.
Kucharski, R. Maleszka, R. (2020) Exploring DNA methylation diversity in the honey bee brain by ultra-deep amplicon sequencing. Epigenomes 4 (2), 10 3
Wojciechowski M, Lowe R, Maleszka J, Conn D, Maleszka R, Hurd PJ. (2018) Phenotypically distinct female castes in honey bees are defined by alternative chromatin states during larval development. Genome Res. 28:1532-1542.
Wedd, L, Kucharski R, Maleszka R (2016) Differentially methylated obligatory epialleles modulate context-dependent LAM gene expression in the honey bee Apis mellifera. Epigenetics. 11: 1-10.
- Foret S, Kucharski R, Pellegrini M, Feng S, Jacobsen SE, Robinson GE, Maleszka R (2012) DNA methylation dynamics, metabolic fluxes, gene splicing, and alternative phenotypes in honey bees. Proc Natl Acad Sci U S A. 109:4968-4973
- Lyko F, Maleszka R. (2011) Insects as innovative models for functional studies of DNA methylation.Trends in Genetics. 27:127-131 [Cover article]
- Lyko, F, Foret, S, Kucharski, R, Wolf, S, Falckenhayn, C, Maleszka, R (2010) The Honey Bee Epigenomes: Differential Methylation of Brain DNA in Queens and Workers. PloS Biol. 8, e1000506.
- Maleszka as a member of the Nasonia Genome Working Group (2010) Functional and evolutionary insights from the genomes of three parasitoid Nasonia species. Science. 327:343-348
- Maleszka, R (2008) Epigenetic integration of environmental and genomic signals in honey bees: the critical interplay of nutritional, brain and reproductive networks. Epigenetics. 3, 188-192
- Kucharski, R, Maleszka, J., Foret, S. Maleszka, R (2008) Nutritional control of reproductive status in honey bees via DNA methylation. Science. 319:1827-1830.
- Maleszka, R. as a member of the Tribolium Genome Sequencing Consortium (2008) The genome of the model beetle and pest Tribolium castaneum. Nature, 452, 949-955.
- Barron, A.B., Maleszka, R., Vander Meer, R. and G.E. Robinson. (2007) Octopamine modulates honey bee dance behavior. Proc Natl Acad Sci U S A. 104, 1703-1707.
- Wang, Y, Jorda, M. Jones, PL, Maleszka, R, et al (2006) Functional CpG Methylation System in a Social Insect. Science. 314, 645-647.
- Drapeau, M.D., Albert, S., Kucharski, R, Prusko, C., Maleszka, R. (2006) Evolution of the Yellow / Major Royal Jelly Protein family and the emergence of social behavior in honeybees. Genome Res. 16, 1385-1394. [Cover article]
- Maleszka as a member of the Honey Bee Genome Consortium (2006) Insights into social insects from the genome of the honey bee Apis mellifera. Nature, 443, 931-949. [Cover article]
- Foret, S. and Maleszka, R. (2006) Function and evolution of a gene family encoding odorant binding-like proteins in a social insect, the honey bee (Apis mellifera). Genome Res. 16, 1404- 1413.