Fahrer Group - Immunology

The Group is focused on two main areas of research at the moment:

  1. A very simple and inexpensive cancer immunotherapy treatment I have come up with, involving a single injection of an immune stimulant into a tumour.
  2. A bioinformatics study looking for novel proteins in different genomes. We have just recently around 2000 novel proteins from humans and mice.

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Selected publications

  • Wilson L.O., Spriggs A, Taylor J.M., Fahrer A.M. A novel splicing outcome reveals more than 2000 new mammalian protein isoforms.Bioinformatics. 2014 Jan 15;30(2):151-6
  • Wilson, L.O; Fahrer, A.M. (2013) Condensins, chromatin remodeling and gene transcription, Chromatin Remodelling, Dr Danuta Radzioch (Ed.), ISBN: 978-953-51-1087-3 InTech. Also available from InTech Open
  • Fahrer, Aude M, (2012). A proposal for a simple and inexpensive therapeutic cancer vaccine, Immunology and Cell Biology 90 (3) 310-313
  • Theodoratos, Angelo; Wilson, Laurence O. W.; Gosling, Katharine M.; et al. (2012) Splice variants of the condensin II gene Ncaph2 include alternative reading frame translations of exon 1, Febs Journal 279 (8) 1422-1432
  • Theodoratos, A; Whittle, B; Enders, A; et al. (2010), Mouse strains with point mutations in TAP1 and TAP2, Immunology and Cell Biology 88 (1) 72-78
  • Gosling, KM; Goodnow, CC; Verma, NK; et al (2008), Defective T-cell function leading to reduced antibody production in a kleisin-beta mutant mouse, Immunology 125 (2) 208-217
  • Gosling, KM; Makaroff, LE; Theodoratos, A; et al (2007) A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell development, Proceedings of the National Academy Of Sciences of the United States Of America 104 (30) 12445-12450
  • Liston, A; Lesage, S; Gray, DHD; et al, (2004) Generalized resistance to thymic deletion in the NOD mouse: A polygenic trait characterized by defective induction of Bim, Immunity 21 (6) 817-830
  • Fahrer, AM; Bazan, JF; Papathanasiou, P; et al (2001) A genomic view of immunology, Nature 409 (6822) 836-838
  • Fahrer, AM; Konigshofer, Y; Kerr, EM; et al,(2001) Attributes of gamma delta intraepithelial lymphocytes as suggested by their transcriptional profile, Proceedings of the National Academy Of Sciences of the United States Of America 98 (18) 10261-10266.

All publications

Dr Diana Stojanovski, University of Melbourne

Mitochondrial Protein Import in Health and Disease

Event | Thu 17 October 2019
Mitochondrial function and cell viability require a functional and healthy mitochondrial proteome.

Chromatin structure and epigenetics in Plasmodium falciparum

Event | Thu 27 June 2019

 The genome of the malaria parasite Plasmodium falciparum is maintained primarily as transcriptionally competent, euchromatin with only rest

Roles of IgM in immunity to malaria in humans

Event | Thu 13 June 2019

A key mediator of protective immunity to malaria is antibodies that block merozoite invasion of the RBC.

Identifying the drug binding site(s) of P-glycoprotein

Event | Thu 7 February 2019

The multidrug resistance protein P-glycoprotein (P-gp) is characterized by its ability to bind and/or transport many chemically, structurally, and

PhD Exit Seminar Complete Freund’s Adjuvant (CFA) as an effective cancer immunotherapy.

Event | Wed 19 December 2018

Intratumoural injection of complete Freund’s adjuvant (CFA), an emulsion of heat-killed Mycobacterium butyricum, is a novel and effective ca

Bacteria blasting cancer treatment shows promise

Story | Tuesday 28 September 2021
A low-cost, non-toxic cancer treatment has been developed by researchers at The Australian National University (ANU). The treatment uses dead bacteria to help kick-start the immune system and shrink cancer.

Aude Fahrer, putting cancer on trial

Story | Tuesday 18 December 2018
Aude Fahrer's work aims to activate the immune cells responsible for attacking cancer, in a simple, low cost way.

Putting cancer on trial

Story | Friday 20 October 2017

Erin Andrew wins ANU 3 Minute Thesis competition

Story | Thursday 7 September 2017
Erin Andrew from the Research School of Biology (RSB) has won the 2017 ANU 3MT (3 Minute Thesis) competition