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Saliba Group - Physiology and biochemistry of the malaria parasite
The Saliba Group is investigating vitamin utilisation pathways in the red blood cell stage of the human malaria parasite Plasmodium falciparum. We are investigating these pathways as potential drug targets for new antimalarials.
Group Leader
Research Assistant
Honours Student
PhB Student
PhD Students
Ojo-Ajogu Akuh
Dominik Fachet
Imam (Toni) Fathoni
Ayman Hemasa- Vanessa Howieson
Xiangning (Christine) Liu
Technical Assistant
| Project | Status |
|---|---|
| Vitamin utilisation by malaria parasites | Current |
Publications
Striving toward malaria eradication, by Christina Spry
Story | Sunday 16 August 2020
Striving toward malaria eradication: Development of a single drug to kill malaria parasites and the mosquitoes that transmit them.
Challenging the host-parasite binary
Story | Monday 10 August 2020
Tunan (Nicole) Yu discusses Horwitz and Wilcox (2005) and taking a multi-faceted view towards parasites to manage disease risk.
BSB Seminar Series: The Antimalarial Peroxide Artemisinin and Derivatives: Mechanism of Action - The "Heme Activation" Hypothesis vs. Oxidant Properties
Event | Thu 21 November 2024
Over 50 years ago, the active principle 青蒿素 qīng hāo sū or artemisinin was isolated in pure crystal-line form from the leaves of the Chinese traditional herb 青蒿 qīng hāo - Artemisia annua - by Chinese groups working under the remarkable Project 523 during the latter stages of the Chinese Cultural Revolution.
BSB PhD Exit Seminar: Targeting Thiamine (Vitamin B1) Metabolism and Utilisation in Plasmodium
Event | Thu 18 July 2024
Malaria is a significant disease in Africa, certain countries in Asia, and Central and South America. In 2022, malaria infected approximately 233 million people and caused 608,000 death.
BSB PhD Exit Seminar: Characterising aspects of the CoA biosynthesis pathway in P. falciparum and T. gondii
Event | Thu 2 June 2022
Malaria is an ancient disease leading to the death of more than half a million people every year.
Feeling hot in here: thermotolerance and drug sensitivity in malaria parasites
Event | Fri 28 February 2020
Audrey Odom John, Chief of the Division of Infectious Diseases at Children’s Hospital of Philadelphia. A physician-scientist, Dr. John’s NIH-funded research has focused on Plasmodium falciparum malaria parasites, with a particular interest in targeting parasite metabolism to identify novel targets for drug development
Piezo channels: tension, tethers and transduction
Event | Thu 26 July 2018
Mechanosensitive channels are fundamental molecular components of mechanosensory systems in all organisms.
