Aude Fahrer

Group membership

Dr Fahrer's major research interests are in immunology, cancer immunotherapy and bioinformatics. Aude Fahrer received her B.Sc. (Hons.) and Ph.D. degrees from the University of Melbourne, in viral immunology. Her first postdoctoral position was at Stanford University U.S.A.. During this time she published on gamma delta T cells and also in the field of oral tolerance and was able to make use of several emerging technologies, in particular MHC tetramers for staining antigen-specific T cells, and microarray technology, working in the labs at Affymetrix. Her second postdoctoral position was at the John Curtin School at ANU, where she worked on mouse models of immunological defects, identifying the first mutation in a chromosome condensin protein leading to defective T cell development. Her laboratory at the Research School of Biology currently works on two areas: 1) The characterisation of novel proteins involved in immunology and cancer, following our publication of over 2000 predicted novel proteins in the human and mouse genomes. 2) The development of a novel cancer immunotherapy (for which clinical trial approval has recently been granted).

Dr. Fahrer also has a strong commitment to teaching. She currently convenes the third year course "BIOL3141 Infection and immunity", and also lectures to first year biology, third year immunology, and to medical school students.

Selected publications

  • Wilson L.O., Spriggs A, Taylor J.M., Fahrer A.M. A novel splicing outcome reveals more than 2000 new mammalian protein isoforms.Bioinformatics. 2014 Jan 15;30(2):151-6
  • Wilson, L.O; Fahrer, A.M. (2013) Condensins, chromatin remodeling and gene transcription, Chromatin Remodelling, Dr Danuta Radzioch (Ed.), ISBN: 978-953-51-1087-3 InTech. Also available from InTech Open
  • Fahrer, Aude M, (2012). A proposal for a simple and inexpensive therapeutic cancer vaccine, Immunology and Cell Biology 90 (3) 310-313
  • Theodoratos, Angelo; Wilson, Laurence O. W.; Gosling, Katharine M.; et al. (2012) Splice variants of the condensin II gene Ncaph2 include alternative reading frame translations of exon 1, Febs Journal 279 (8) 1422-1432
  • Theodoratos, A; Whittle, B; Enders, A; et al. (2010), Mouse strains with point mutations in TAP1 and TAP2, Immunology and Cell Biology 88 (1) 72-78
  • Gosling, KM; Goodnow, CC; Verma, NK; et al (2008), Defective T-cell function leading to reduced antibody production in a kleisin-beta mutant mouse, Immunology 125 (2) 208-217
  • Gosling, KM; Makaroff, LE; Theodoratos, A; et al (2007) A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell development, Proceedings of the National Academy Of Sciences of the United States Of America 104 (30) 12445-12450
  • Liston, A; Lesage, S; Gray, DHD; et al, (2004) Generalized resistance to thymic deletion in the NOD mouse: A polygenic trait characterized by defective induction of Bim, Immunity 21 (6) 817-830
  • Fahrer, AM; Bazan, JF; Papathanasiou, P; et al (2001) A genomic view of immunology, Nature 409 (6822) 836-838
  • Fahrer, AM; Konigshofer, Y; Kerr, EM; et al,(2001) Attributes of gamma delta intraepithelial lymphocytes as suggested by their transcriptional profile, Proceedings of the National Academy Of Sciences of the United States Of America 98 (18) 10261-10266.

All publications

  • BIOL3141 Infection and Immunity (Convenor)
  • BIOL3144 Molecular Immunology
  • BIOL1004 Biology 2: Molecular and Cell Biology
  • Medical School (Immunology)