Plasmodium falciparum lipid metabolism as a target for malaria intervention strategies
The intracellular life-style of Plasmodium poses particular challenges for meeting the parasite's demand for lipids. The roles of lipids include membrane components, energy storage and signalling. In this project we will use cutting-edge bioinformatic to model the lipid flow and biochemical, imaging and genetic approaches to identify, characterise and validate malaria lipids as novel drug targets.
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The intracellular life-style of Plasmodium poses particular challenges for meeting the parasite's demand for lipids. The roles of lipids include membrane components, energy storage and signalling. In this project we will use cutting-edge bioinformatic to model the lipid flow and biochemical, imaging and genetic approaches to identify, characterise and validate malaria lipids as novel drug targets.
This project is part of the Crossing Boundaries: Molecular Interactions in Malaria Graduate School. Participants study at both ANU and the Humboldt University in Berlin, earning a dual degree. Find out more.
Photo credit: Sharyn Wragg. Graphic: Maier lab/M. Rug
