Biomedical Science and Biochemistry Seminar Series
Seminars from the RSB Division of Biomedical Science and Biochemistry.
21
Nov
2024
1pm 21 November 2024
Richard K Haynes, Senior Principal Research Fellow, Rural Health Research Institute, Charles Sturt University
Over 50 years ago, the active principle 青蒿素 qīng hāo sū or artemisinin was isolated in pure crystal-line form from the leaves of the Chinese traditional herb 青蒿 qīng hāo - Artemisia annua - by Chinese groups working under the remarkable Project 523 during the latter stages of the Chinese Cultural Revolution.
BSB Seminar Series: The Antimalarial Peroxide Artemisinin and Derivatives: Mechanism of Action - The "Heme Activation" Hypothesis vs. Oxidant Properties
Over 50 years ago, the active principle 青蒿素 qīng hāo sū or artemisinin was isolated in pure crystal-line form from the leaves of the Chinese traditional herb 青蒿 qīng hāo - Artemisia annua - by Chinese groups working under the remarkable Project 523 during the latter stages of the Chinese Cultural Revolution. . More information here: https://biology.anu.edu.au/news-events/events/bsb-seminar-series-antimalarial-peroxide-artemisinin-and-derivatives-mechanism
2024-11-21 02:00:00Z
2024-11-21 02:00:00Z
Please note: this seminar will be held in the Eucalyptus Seminar Rm and via Zoom, details are included below.
Eucalyptus Seminar Room, S205,
Level 2, RN Robertson Bldg (46)
Please click the link below to join the webinar:
https://anu.zoom.us/j/88695849855?pwd=iA0boLxaiIbPiOk8aK5bm5F2Q9coPK.1
Webinar ID: 886 9584 9855
Passcode: 810334
Canberra time: please check your local time & date if you are watching from elsewhere.
13
Feb
2025
BSB Seminar Series
TBA. More information here: https://biology.anu.edu.au/news-events/events/bsb-seminar-series-0
2025-02-13 02:00:00Z
2025-02-13 02:00:00Z
Please note: this seminar will be held in the Eucalyptus Seminar Rm and via Zoom, details are included below.
Eucalyptus Seminar Room, S205,
Level 2, RN Robertson Bldg (46)
Please click the link below to join the webinar: TBA
Webinar ID: TBA
Passcode: TBA
Canberra time: please check your local time & date if you are watching from elsewhere.
Past events
07
Nov
2024
BSB Seminar Series: Uncovering therapeutic vulnerabilities in gastric cancer »
Dr Buchert will present two vignettes highlighting his group’s research in gastric cancer.
26
Sep
2024
BSB PhD Exit Seminar: Decoding the Regenerative Landscape: Insights from Sponge Single-Cell Transcriptomics »
Di has established the first single-cell atlas for calcareous sponges using an endemic species of Australia, Sycon capricorn. His study reinforces the utility of the Sycon sponge as a model to explore a range of biological processes, such as wound healing.
12
Sep
2024
BSB Seminar Series: Designing teaching activities that encourage and support peer-based problem-solving and data analysis in large subjects »
In this seminar, Dr Hayley Bugeja will tell the story of the development of interactive workshops in a large second year genetics subject, which were iteratively designed over several years (pre and post pandemic).
01
Aug
2024
BSB PhD Exit Seminar: Investigating Lipid Modulation of Ion Channels Using Molecular Dynamics Simulations »
Ion channels are the molecular gatekeepers of our cells, activating in response to diverse stimuli to facilitate the movement of ions and solutes across biological membranes.
18
Jul
2024
BSB PhD Exit Seminar: Targeting Thiamine (Vitamin B1) Metabolism and Utilisation in Plasmodium »
Malaria is a significant disease in Africa, certain countries in Asia, and Central and South America. In 2022, malaria infected approximately 233 million people and caused 608,000 death.
04
Apr
2024
BSB Seminar Series: My life with membrane proteins: taming membrane transporters »
A lipid bilayer is a vital component of the cell. It is selectively permeable, allowing only ions and organic molecules to pass through. Ions and solutes are transported by membrane transporters. Dysfunction of such proteins can lead to physiological disorders.
28
Mar
2024
BSB Seminar Series: RSB Precision Fermentation Facility »
Discover the capabilities of the new Precision Fermentation Facility that has been established at RSB, including an overview of the equipment, its capabilities and potential applications.
15
Feb
2024
BSB Seminar Series: Discovery and characterization of JNT-517, a first-in-class inhibitor of SLC6A19 for the treatment of phenylketonuria »
Toxic accumulation of phenylalanine underlies the neurological deficits and morbidity in phenylketonuria (PKU). Despite availability of treatment options for PKU patients, high unmet need remains for safe and convenient therapies that work across a broad cross section of PKU patients and allow for diet normalization.
15
Dec
2023
BSB PhD Exit Seminar: Cellular and molecular characterisation of regeneration in calcareous sponges and corals »
Regeneration is the natural ability to restore or replace damaged or lost body parts following severe injury. Regenerative abilities vary strongly across and within most bilaterian phyla.
17
Nov
2023
BSB Seminar Series: Room temperature DNA storage to enhanced Drug bioavailability: Magic molecules Ionic Liquids in action »
DNA stability is a prerequisite in many of its applications, ranging from DNA-based vaccine, data storage to gene therapy. However, the existing strategies to enhance the DNA stability are ineffective and limited in scope.
14
Nov
2023
Joint PS and BSB Seminar - Synthetic control of peptide and protein architectures »
Synthetic chemistry and synthetic biology offer complementary tools for manipulating the 3D architecture and function of biomolecules. I will outline two different projects that exemplify our hybrid chemical biology approach, highlighting divergent applications in catalysis and cancer therapy.
02
Nov
2023
BSB Seminar Series: Malaria parasite invasion of human red blood cells and the insights we can obtain from 4D imaging »
Associate Professor Kelly Roger's team has built a lattice light sheet microscope which was instrumental in the discovery that mitochondrial DNA is released during apoptosis through BAK and BAX pores in the outer mitochondrial membrane.
11
Sep
2023
BSB Seminar: A chemogenetics platform for antimalarial drug target identification and hit discovery »
Malaria is a major global health problem, with 247 million cases and 619,000 deaths estimated in 2021. Antimalarial drugs are critical for malaria treatment and eradication efforts.
20
Jul
2023
BSB Seminar: Development and characterisation of novel antimalarial chemotypes from the Janssen Jumpstarter library »
Malaria is a devastating disease caused by the Plasmodium parasite. Due to the threat of emerging drug resistance, the current arsenal of clinically used artemisinin combination therapies and drug candidates undergoing clinical assessment may not be sufficient in eliminating the disease.
06
Jul
2023
BSB Seminar: Deconstructing Solid Tumour Heterogeneity: The Matrix Perspective »
Homeostasis of the extracellular matrix is critical for correct organ and tissue function. Both the biochemical and biomechanical properties of the matrix contribute to modulating the behaviour of resident cells and are more than just passive bystanders.