Voltage-gated sodium (Nav) channels are essential for electrical signaling in excitable tissues, including the brain, heart, and muscles.

Many proteins migrate from cytoplasm to nucleus through their recognition by specialist receptors known as importins (IMPs).

Bacteriophages, with their intricate and highly specialized structures, represent some of the most fascinating architectures in the biological world. These viral entities serve as a sustainable and eco-friendly alternative to chemical treatments in agriculture and as biocontrol agents against bacterial pathogens.

Natural products have long been celebrated as a treasure trove of therapeutic agents, serving as the foundation for many life-saving drugs. This general talk outlines possible approaches to the discovery and development of small molecule therapeutics for the treatment of inflammation and infectious diseases.

This presentation highlights high-resolution cryo-EM structures of C. albicans Cdr1 in various substrate-bound states, with and without nucleotides, resolved at 3.45–3.74 Å.

Making key insights into antimalarial resistance mechanisms and delineate the utility of cutting-edge computational approaches that will go on to inform future drug design strategies and efforts.

Over 50 years ago, the active principle 青蒿素 qīng hāo sū or artemisinin was isolated in pure crystal-line form from the leaves of the Chinese traditional herb 青蒿 qīng hāo - Artemisia annua - by Chinese groups working under the remarkable Project 523 during the latter stages of the Chinese Cultural Revolution.

Dr Buchert will present two vignettes highlighting his group’s research in gastric cancer.

Di has established the first single-cell atlas for calcareous sponges using an endemic species of Australia, Sycon capricorn. His study reinforces the utility of the Sycon sponge as a model to explore a range of biological processes, such as wound healing.

In this seminar, Dr Hayley Bugeja will tell the story of the development of interactive workshops in a large second year genetics subject, which were iteratively designed over several years (pre and post pandemic).

Ion channels are the molecular gatekeepers of our cells, activating in response to diverse stimuli to facilitate the movement of ions and solutes across biological membranes.

Malaria is a significant disease in Africa, certain countries in Asia, and Central and South America. In 2022, malaria infected approximately 233 million people and caused 608,000 death.