Stephen Fairweather

Research interests

Membrane Physiology and Transporters

Protein-Protein Interactions

Electrophysiology

Amino Acid Metabolism

Membrane Transporter Phamacology

Protein Molecular Dynamic Simulations

  • Broer, S & Fairweather, S 2019, 'Amino Acid Transport Across the Mammalian Intestine', Comprehensive Physiology, vol. 9, no. 1, pp. 343-373pp.
  • Javed, K & Fairweather, S 2019, 'Amino acid transporters in the regulation of insulin secretion and signalling', Biochemical Society Transactions, vol. 47, no. 2, pp. 571-590.
  • Parker, K, Fairweather, S, Rajendran, E et al 2019, 'The tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family', PLoS Pathogens, 15, e1007577.
  • Broer, A, Fairweather, S & Broer, S 2018, 'Disruption of Amino Acid Homeostasis by Novel ASCT2 Inhibitors Involves Multiple Targets', Frontiers in Pharmacology, vol. 9, no. 785, pp. 1-11pp.
  • Cheng, Q, Shah, N, Broer, A et al 2017, 'Identification of novel inhibitors of the amino acid transporter B0AT1 (SLC6A19), a potential target to induce protein restriction and to treat type 2 diabetes', British Journal of Pharmacology, vol. 174, no. 6, pp. 468-482pp.
  • Rajendran, E, Hapuarachchi, S, Miller, C et al 2017, 'Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites', Nature Communications, 8:14455. doi: 10.1038/ncomms14455.
  • Morton, S, Chaston, D, Howitt, L et al 2015, 'Loss of functional endothelial connexin40 results in exercise-induced hypertension in mice', Hypertension, vol. 65, no. 3, pp. 662-U362.
  • Fairweather, S, Broer, A, Subramanian, N, Tumer, E, Cheng, Q, Schmoll, D, O'Mara, ML, Bröer, S. 2015, 'Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin', Journal of Biological Chemistry, vol. 290, no. 40, pp. 24308-24325.
  • Fairweather, S, Broer, A, O'Mara, M et al 2012, 'Intestinal peptidases form functional complexes with the neutral amino acid transporter B0AT1', Biochemical Journal, vol. 446, no. 1, pp. 135-148.