Kai Xun Chan completed his Bachelor's degree in Biotechnology with First Class Honours and a University Medal in Biology in 2010 at the Australian National University (ANU). In December 2015 he completed his PhD in Plant Sciences at ANU, elucidating the structural regulation of the chloroplast signaling protein SAL1. After postdoctoral stints at the ANU and at the VIB-UGent Center for Plant Systems Biology in Belgium as an FWO Research Fellow, Kai returned to ANU in 2022 as a Group Leader and ARC DECRA Fellow.
Throughout his short academic career so far, Kai has won numerous awards including the 2017 ACT Scientist of the Year, 2017 ACT Young Tall Poppy Award, and an ANU JG Crawford Medal, the ANU's premier award for graduate excellence. He is the recipient of several competitive fellowships including an ARC DECRA, FWO Research Fellowship and Marie Curie Postdoctoral Fellowship from the European Commission. He is also funded by two industry grants from ANU-UC Connect Ventures.
Kai has published in various international peer-reviewed journals including PNAS, eLife, Annual Review of Plant Biology, and Trends in Plant Science (see full list below). He also serves as a reviewer for specialist plant research journals including The Plant Cell, Plant Physiology, The Plant Journal and Journal of Experimental Botany.
- Zhao, C, Wang, Y, Chan, K et al. 2019, 'Evolution of chloroplast retrograde signaling facilitates green plant adaptation to land', PNAS - Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 11, pp. 5015-5020.
- Phua, S, Pornsiriwong, W, Chan, K et al. 2018, 'Development of strategies for genetic manipulation and fine-tuning of a chloroplast retrograde signal 3'-phosphoadenosine 5'-phosphate', Plant Direct, vol. 2, no. 1, pp. 1-15.
- Phua, S, Yan, D, Chan, K et al. 2018, 'The arabidopsis SAL1-PAP pathway: A case study for integrating chloroplast retrograde, light and hormonal signaling in modulating plant growth and development?', Frontiers in Plant Science, vol. 9, no. 1171, pp. 1-8.
- Chan, K, Mabbitt, P, Phua, S et al. 2016, 'Sensing and signaling of oxidative stress in chloroplasts by inactivation of the SAL1 phosphoadenosine phosphatase', PNAS - Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 31, pp. E4567-E4576.
- Pornsiriwong, W, Estavillo, G, Chan, K ... Phua, S, et al 2017, 'A chloroplast retrograde signal, 3'-phosphoadenosine 5'-phosphate, acts as a secondary messenger in abscisic acid signaling in stomatal closure and germination', eLife, vol. 6, no. -, pp. 1-34pp.
- Zhang , X, Ivanova, A, Vandepoele, K et al. 2017, 'The transcription factor MYB29 is a regulator of alternative oxidase1a', Plant Physiology, vol. 173, no. 3, pp. 1824-1843.
- Chan, K, Phua, S, Crisp, P et al. 2016, 'Learning the Languages of the Chloroplast: Retrograde Signaling and Beyond', Annual Review of Plant Biology, vol. 67, pp. 25-53.
- Bruggeman, Q, Mazubert, C, Prunier, F ... Phua, S, et al 2016, 'Chloroplast activity and 3' phosphadenosine 5'phosphate signaling regulate programmed cell death in Arabidopsis', Plant Physiology, vol. 170, no. 3, pp. 1745-1756.
- Van Norman, J, Zhang, J, Cazzonelli, C et al. 2014, 'Periodic root branching in Arabidopsis requires synthesis of an uncharacterized carotenoid derivative', National Academy of Sciences. Proceedings, vol. 111, no. 13, pp. E1300-E1309.
- Chan, K, Wirtz, M, Phua, S et al. 2013, 'Balancing metabolites in drought: the sulfur assimilation conundrum', Trends in Plant Science, vol. 18, no. 1, pp. 18-29.
- Estavillo, G, Chan, K, Phua, S et al. 2013, 'Reconsidering the nature and mode of action of metabolite retrograde signals from the chloroplast', Frontiers in Plant Science, vol. 3, no. Article 300, pp. 1-9.
- Chan, K, Crisp, P, Estavillo, G et al. 2010, 'Chloroplast-to-nucleus communication; Current knowledge, experimental strategies and relationship to drought stress signaling', Plant Signaling & Behavior, vol. 5, no. 12, pp. 1575-1582.
Lecturing and Research Supervision
- Co-convener and lecturer for BIOL3107 / BIOL6107 (Advances in Medical and Plant Biochemistry)
- Supervisor for undergraduate, Honours, Masters and PhD projects - see Projects tab for current projects