PS Webinar Series: Keeping genes alive: the central role of terminators in protecting transgenes from silencing

Gene silencing induced by small RNAs (sRNAs) is an important mechanism responsible for many crucial physiological responses in plants, such as genome integrity, defense against virus, adaptation to biotic and abiotic stresses and regulation of development.

schedule Date & time
Date/time
7 Oct 2020 12:00pm
person Speaker

Speakers

Dr. Felipe Fenselau de Felippes – Senior Research Associate at CAB, QUT
next_week Event series
contact_support Contact

Content navigation

Description

Abstract -Gene silencing induced by small RNAs (sRNAs) is an important mechanism responsible for many crucial physiological responses in plants, such as genome integrity, defense against virus, adaptation to biotic and abiotic stresses and regulation of development. sRNAs also play a central role in the stability of transgenes, which compared to endogenes, are particularly susceptible to silencing.

In my talk, I will focus on some of our recent research showing how terminators and the process of transcription termination can influence the production of sRNAs from a given locus, directly impacting the stability and expression of a gene, and how plants might use this mechanism to differentiate between exogenous sequences and their own genes.

Biography - Felipe majored in Biology and did his Master in Genetics and Molecular Biology at the Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil. He then joined the Max Planck Institute for Developmental Biology (Tübingen, Germany) as a PhD student, working in different aspects concerning small RNAs (sRNAs), such as the origin and evolution of microRNAs, mobility of sRNAs and the biogenesis of tasiRNAs. He continued his research with sRNAs as a postdoctoral fellow at the Swiss Federal Institute of Technology (ETH) in Zurich, Switzerland. Since 2017, Felipe works at the group of Prof. Peter Waterhouse at QUT studying the role of sRNAs in the recognition of self and non-self in plants, among other features of the sRNA biology.

Location

You are invited to a Zoom webinar.
When: Oct 7, 2020 12:00 PM Canberra, Melbourne, Sydney
Topic: Dr. Felipe Fenselau de Felippes webinar

Please click the link below to join the webinar:
https://anu.zoom.us/j/82323023401?pwd=blNsWDhCSElybXBvM1ZGQUp4K2cxUT09

Webinar ID: 823 2302 3401
Passcode: 010981

Or iPhone one-tap :
    Australia: +61871501149,,82323023401#,,,,,,0#,,010981#  or +61280156011,,82323023401#,,,,,,0#,,010981#
Or Telephone:
    Dial(for higher quality, dial a number based on your current location):
        Australia: +61 8 7150 1149  or +61 2 8015 6011  or +61 3 7018 2005  or +61 7 3185 3730  or +61 8 6119 3900

    International numbers available: https://anu.zoom.us/u/kiLnKkl9o

Or an H.323/SIP room system:
    H.323: 113.197.7.201 or 113.197.7.202
    Meeting ID: 823 2302 3401
    Passcode: 010981
    SIP: 82323023401@113.197.7.201 or 82323023401@113.197.7.202
    Passcode: 010981

Upcoming events in this series

MM
23 Sep 2025 | 2pm

Mitochondrial biogenesis in plants is a complex and tightly regulated process crucial for cellular energy production, metabolic regulation, and stress responses.

View the event
Sareena Sahab
31 Oct 2025 | 12pm

This presentation will explore the application of precision gene editing technologies for trait enhancement in grain crops, with a focus on the integrated platform capabilities developed at Agriculture Victoria (AgVic).

View the event
James Nix
14 Nov 2025 | 3:30pm

Cyclic electron flow (CEF) around PSI is essential for balancing ATP/NADPH supply and protecting photosystems under fluctuating light.

View the event
John Kean
1 Dec 2025 | 12pm

This talk will revisit and contextualise the invasion predicted by Cellarius within a framework of biosecurity risk assessment.

View the event