ARC Discovery Project


DP140101794  Professor Adrienne R Hardham

  • 2014 $138,000.00
  • 2015 $130,000.00
  • 2016 $140,000.00
  • Total $408,000.00


Administering Organisation: The Australian National University

Project Summary

A critical aspect of plant defence is protection of plant cell walls against pathogen penetration. Plants achieve this through the activity of inhibitors that specifically target pathogen cell wall degrading enzymes. These inhibitor proteins have great potential in engineering improved plant resistance to disease but their use is hampered by limited knowledge of their deployment and specificity. This project will produce an in-depth understanding of the identity, regulation and role of plant inhibitors that combat attack by destructive pathogens in the genus Phytophthora. It will not only address the serious problem of Phytophthora diseases in Australia but will also apply to plant defence against other pathogens.