Maleszka Lab - From molecules to behaviour

Bee and molecule

We are investigating diverse epigenetic mechanisms in the context of behaviour and developmental plasticity, mainly using the honey bee model, but we also have close interactions with labs working on other interesting systems.



Ryszard Maleszka

Ryszard Maleszka
Ryszard Maleszka received his MSc and a PhD from the Department of Genetics, University of Warsaw and has done postdoctoral...

Divisional Visitor

Honours Student

PhD Student

Postdoctoral Scientist

Special Project Student

Technical Officer

Visiting Fellow


Open to students


Selected publications

  • Foret S, Kucharski R, Pellegrini M, Feng S, Jacobsen SE, Robinson GE, Maleszka R (2012) DNA methylation dynamics, metabolic fluxes, gene splicing, and alternative phenotypes in honey bees. Proc Natl Acad Sci U S A. 109:4968-4973
  • Lyko F, Maleszka R. (2011) Insects as innovative models for functional studies of DNA methylation.Trends in Genetics. 27:127-131 [Cover article]
  • Lyko, F, Foret, S, Kucharski, R, Wolf, S, Falckenhayn, C, Maleszka, R (2010) The Honey Bee Epigenomes: Differential Methylation of Brain DNA in Queens and Workers. PloS Biol8, e1000506.
  • Maleszka as a member of the Nasonia Genome Working Group (2010) Functional and evolutionary insights from the genomes of three parasitoid Nasonia species. Science. 327:343-348
  • Barron, AB, Maleszka, R, Helliwell, PG & Robinson, GE (2009) Effects of Cocaine on Honey Bee Dance Behaviour. J. Exp. Biol. 211, 163-168.
  • Maleszka, R (2008) Epigenetic integration of environmental and genomic signals in honey bees: the critical interplay of nutritional, brain and reproductive networks. Epigenetics. 3, 188-192
  • Kucharski, R, Maleszka, J., Foret, S. Maleszka, R (2008) Nutritional control of reproductive status in honey bees via DNA methylation. Science. 319:1827-1830.
  • Maleszka, R. as a member of the Tribolium Genome Sequencing Consortium (2008) The genome of the model beetle and pest Tribolium castaneum. Nature, 452, 949-955.
  • Barron, A.B., Maleszka, R., Vander Meer, R. and G.E. Robinson. (2007) Octopamine modulates honey bee dance behavior. Proc Natl Acad Sci U S A. 104, 1703-1707.
  • Wang, Y, Jorda, M. Jones, PL, Maleszka, R, et al (2006) Functional CpG Methylation System in a Social Insect. Science. 314, 645-647.
  • Drapeau, M.D., Albert, S., Kucharski, R, Prusko, C., Maleszka, R. (2006) Evolution of the Yellow / Major Royal Jelly Protein family and the emergence of social behavior in honeybees. Genome Res. 16, 1385-1394. [Cover article]
  • Maleszka as a member of the Honey Bee Genome Consortium (2006) Insights into social insects from the genome of the honey bee Apis melliferaNature, 443, 931-949. [Cover article]
  • Foret, S. and Maleszka, R. (2006) Function and evolution of a gene family encoding odorant binding-like proteins in a social insect, the honey bee (Apis mellifera). Genome Res. 16, 1404- 1413.



Ryszard Maleszka

Lab research focus

Updated:  30 May 2016/Responsible Officer:  Director RSB/Page Contact:  Webmaster RSB