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PROJECT SPOTLIGHT
Cellular adaptations that allow the transmission and survival of Plasmodium falciparum when taken up by the mosquito
The environment encountered by the malaria parasite in the mosquito is very different from the surrounding in the human host (temperature, available nutrients, immune system,....). We are looking at the necessary differentiation a malaria parasite undergoes before it can be taken up from human blood by the mosquito vector. These changes are irreversible and essential for transmission.