Birhanu Ayelign Jemere

Group membership

Birhanu Ayelign is currently a Ph.D. student at Australian National University, Canberra, Australia, working in Professor Fahrer’s group on a Cancer immunotherapy project. He had been working as a full-time academic staff at the University of Gondar, Ethiopia. He has completed his Erasmus Mundus joint master’s degree in Leading International Vaccinology Education accredited by five European Universities: the University Autonoma of Barcelona, the University of Barcelona in Spain, the University of Antwerp in Belgium, the University Jean Monnet of Saint-Étienne, and University Claude Bernard Lyon in France. He graduated Bachelor’s degree in Medical Laboratory Science and a Master of degree in Immunology at the University of Gondar, Ethiopia.

Research interests


  • Immunology,
  • Cancer Immunology, immunotherapy
  • Vaccinology in particular to mRNA vaccine research and development

Andualem H, Lemma M, Keflie A, Workeneh M, Ayelign B, Tassachew Y, Hailu L, Geteneh A, Mihret A, Zewdie M, Howe R. Elevated KIR expression and diminished intensity of CD7 on NK cell subsets among treatment naïve HIV infected Ethiopians. Scientific reports. 2022 Aug 30;12(1):1-0.

Adane G, Lemma M, Geremew D, Sisay T, Tessema MK, Damtie D, Ayelign B. Genetic Polymorphism of Tumor Necrosis Factor-Alpha, Interferon-Gamma and Interleukin-10 and Association With Risk of Mycobacterium Tuberculosis Infection. Journal of Evidence-Based Integrative Medicine. 2021 Apr 23;26:2515690X211006344.

Ayelign B, Negash M, Andualem H, Wondemagegn T, Kassa E, Shibabaw T, Akalu Y, Molla MD. Association of IL-10 (− 1082 A/G) and IL-6 (− 174 G/C) gene polymorphism with type 2 diabetes mellitus in Ethiopia population. BMC endocrine disorders. 2021 Dec;21(1):1-8.

Ayelign B, Akalu Y, Teferi B, Molla MD, Shibabaw T. Helminth induced immunoregulation and novel therapeutic avenue of allergy. Journal of asthma and allergy. 2020;13:439.

Shibabaw T, Molla MD, Teferi B, Ayelign B. Role of IFN and complements system: innate immunity in SARS-CoV-2. Journal of Inflammation Research. 2020;13:507.

Ayelign B, Workneh M, Molla MD, Dessie G. Role of vitamin-D supplementation in TB/HIV co-infected patients. Infection and Drug Resistance. 2020;13:111.

Ayelign B, Jemal M, Negash M, Genetu M, Wondmagegn T, Zeleke AJ, Worku L, Bayih AG, Shumie G, Behaksra SW, Fenta T. Validation of in-house liquid direct agglutination test antigen: the potential diagnostic test in visceral Leishimaniasis endemic areas of Northwest Ethiopia. BMC microbiology. 2020 Dec;20(1):1-

Ayelign B, Negash M, Genetu M, Wondmagegn T, Shibabaw T. Immunological impacts of diabetes on the susceptibility of Mycobacterium tuberculosis. Journal of immunology research. 2019 Oct;2019.

Ayelign B, Genetu M, Wondmagegn T, Adane G, Negash M, Berhane N. TNF-α (− 308) Gene Polymorphism and Type 2 Diabetes Mellitus in Ethiopian Diabetes Patients. Diabetes, metabolic syndrome and obesity: targets and therapy. 2019;12:2453.

Admassu W, Ayelign B, Abebe G, Tadesse M. Detection of Mycobacterium tuberculosis and rifampicin resistance by Xpert® MTB/RIF assay among presumptive tuberculosis cases at Jimma University Medical Center, Southwest Ethiopia. Plos one. 2022 Jan 27;17(1):e0262929.

Akalu Y, Molla MD, Dessie G, Ayelign B. Physiological effect of ghrelin on body systems. International journal of endocrinology. 2020 May 25;2020.

Ayelign B, Workneh M, Molla MD, Dessie G. Role of vitamin-D supplementation in TB/HIV co-infected patients. Infection and Drug Resistance. 2020;13:111.

Dessie G, Ayelign B, Akalu Y, Shibabaw T, Molla MD. Effect of leptin on chronic inflammatory disorders: insights to therapeutic target to prevent further cardiovascular complication. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 2021;14:3307.

Molla MD, Bekele A, Melka DS, Teklemariam MD, Challa F, Ayelign B, Shibabaw T, Akalu Y, Geto Z. Hyperuricemia and Its Associated Factors Among Adult Staff Members of the Ethiopian Public Health Institute, Ethiopia. International Journal of General Medicine. 2021;14:1437.

Molla MD, Dessie G, Akalu Y, Ayelign B. Hepatocellular expression of SIRT1 and its effect on hepatocellular carcinoma progression: a future therapeutic perspective. International journal of hepatology. 2020 Jun 13;2020.

Molla MD, Ayelign B, Dessie G, Geto Z, Admasu TD. Caspase-1 as a regulatory molecule of lipid metabolism. Lipids in Health and Disease. 2020 Dec;19(1):1-7.

Shibabaw T, Teferi B, Molla MD, Ayelign B. Inflammation mediated hepcidin-ferroportin pathway and its therapeutic window in breast cancer. Breast Cancer: Targets and Therapy. 2020;12:165.

Molla MD, Akalu Y, Geto Z, Dagnew B, Ayelign B, Shibabaw T. Role of caspase-1 in the pathogenesis of inflammatory-associated chronic non-communicable diseases. Journal of Inflammation Research. 2020;13:749.

Shibabaw T, Dessie G, Molla MD, Zerihun MF, Ayelign B. Assessment of liver marker enzymes and its association with type 2 diabetes mellitus in Northwest Ethiopia. BMC research notes. 2019 Dec;12(1):1-5.

Ayelign B, Abebe B, Shibeshi A, Meshesha S, Shibabaw T, Addis Z, Gelaw A, Dagnew M. Bacterial isolates and their antimicrobial susceptibility patterns among pediatric patients with urinary tract infections. Turkish journal of urology. 2018 Jan;44(1):62.

Eshetie S, Unakal C, Gelaw A, Ayelign B, Endris M, Moges F. Multidrug-resistant and carbapenemase producing Enterobacteriaceae among patients with urinary tract infection at referral Hospital, Northwest Ethiopia. Antimicrobial resistance and infection control. 2015 Dec;4(1):1-8.