Pawan Parajuli

Profile

Biography

Pawan Parajuli received his MSc from the Department of Biotechnology, Osmania University, India in 2010. After his MSc, he worked as a research assistant at the Nepal Academy of Science and Technology (2011-2012) and Mycobacterial Research Laboratory, the Leprosy Mission Nepal (2012-2015). He was also a visiting lecturer at the SANN international college, Kathmandu, Nepal (2011-2015). He then returned to study in 2016 for a PhD with an Endeavour Scholarships in the Verma Lab. His PhD research aims in understanding the function of bacteriophage-encoded genes in Shigella flexneri evolution, serotype diversification and virulence. He is particularly interested in working at the interface of bioinformatics and lab based functional genomics research.

Research

Research awards

Research interests

Microbial genetics
Functional genomics
Molecular pathogenesis and evolution of emerging infectious diseases

Publications

1. Parajuli P, Deimel LP, Verma NK: Genome analysis of Shigella flexneri serotype 3b strain SFL1520 reveals significant horizontal gene acquisitions including a multidrug resistance cassette, Genome Biology and Evolution, 2019. doi: 10.1093/gbe/evz026. [Epub ahead of print]
2. Parajuli P, Adamski M, Verma NK: Bacteriophages are the major drivers of Shigella flexneri serotype 1c genome plasticity: a complete genome analysis. BMC Genomics 2017, 18(1):722.
3. Hagge DA, Parajuli P, Kunwar CB, Rana D, Thapa R, Neupane KD, Nicholls P, Adams LB, Geluk A, Shah M et al: Opening a Can of Worms: Leprosy Reactions and Complicit Soil-Transmitted Helminths. EBioMedicine 2017, 23:119-124.
4. Walker S. L., Hagge D. A. ,Parajuli P, Nicholls P. G., Lockwood D. N.J. et al. on behalf of the Erythema Nodosum Leprosum International STudy Group: ENLIST 1: an International Multi-Centre Cross-Sectional Study of the Clinical Features of Erythema Nodosum Leprosum. PLOS Neglected Tropical Diseases 2015, 9(9):e0004065
5. Parajuli P, Nisha Rana, Sangita Shrestha, Jyoti Maharjan, Prabina Rana and Jayashree Sijapati: Isolation and Characterization of Bacillus thuringiensis Strains Containing cryi genes from soil samples of Nepal. Asian Journal of Microbiology, Biotechnology and Environmental science 2015, 17(3):99-104
6. Upadhyay A. K. and Parajuli P: Extended spectrum β-lactamase producing multidrug-resistant Klebsiella species isolated at National Medical College and Teaching Hospital, Nepal. Asian J Pharm Clin Res 2013,6 ( 4):161-164

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