Multiple Sequence Optimization Alignment - Heuristic Methods

Date & time

2–3pm 10 October 2018


Eucalyptus Seminar Room, Level 2, RN Robertson Building #46


Professor Jotun Hein, Bioinformatics at the Department of Statistics, University of Oxford


 Terri Richardson
 6125 5070


BSA is a huge field since sequences are presently so abundant. So far Jotun has covered pairwise and multiple alignment optimizing some score function or defined via a heuristic algorithm.   In this lecture Jotun will cover the use of HMMs (Profile, Pairwise, Phylogenetics) as invented in the 90s.  Then, Jotun will discuss sequence comparison, that does not need an alignment (alignment free methods).   A finish with local alignment, probability theory of sequence comparison and database search.

Preliminary slides can be found here.



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