Is the genomic arrangment of the Zic genes crucial for their function?

Date & time

1pm 29 March 2012

Location

Gould Seminar Room Building 116, Daley Rd, ANU

Description

Associate Professor Ruth Arkell,  Evolution, Ecology & Genetics, Research School of Biology

The Arkell laboratory studies the genetic mechanisms that drive gastrulation of the mammalian embryo. Gastrulation is the process that converts a group of pluripotent cells (the inner cell mass of the blastocyst) into the three germ layers (ectoderm, endoderm and mesoderm) from which the entire adult organism is derived. In mammalian embryos gastrulation is concomitant with the establishment of the three embryonic axes (anterior-posterior, dorsal-ventral and left-right) that enables each embryonic cell to acquire a positional address without which differentiation and morphogenesis cannot take place.

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