Riboflavin (also known as vitamin B2) is metabolised into two cofactors (known as flavins) that are essential for flavin-utilising enzymes such as pyridoxine 5-phosphate oxidase and glutathione reductase. In this project the student will make use of in vitro assays and field samples to investigate the riboflavin requirements of the malaria parasite-infected host erythrocyte. Information from this project could lead to the development of novel antimalarials.
This project is part of the Crossing Boundaries: Molecular Interactions in Malaria Graduate School. Participants study at both ANU and the Humboldt University in Berlin, earning a dual degree. Find out more.
Picture credit: Melanie Johnson-Saliba. Graphic credit: Kevin Saliba