Riboflavin requirements by the intraerythrocytic stage of the human malaria parasite Plasmodium falciparum

Description

Riboflavin (also known as vitamin B2) is metabolised into two cofactors (known as flavins) that are essential for flavin-utilising enzymes such as pyridoxine 5-phosphate oxidase and glutathione reductase. In this project the student will make use of in vitro assays and field samples to investigate the riboflavin requirements of the malaria parasite-infected host erythrocyte. Information from this project could lead to the development of novel antimalarials. 

This project is part of the Crossing Boundaries: Molecular Interactions in Malaria Graduate SchoolParticipants study at both ANU and the Humboldt University in Berlin, earning a dual degree. Find out more.

Picture credit: Melanie Johnson-Saliba. Graphic credit: Kevin Saliba

Partnerships

Kevin saliba (ANU, Canberra, Australia) in partnership with Frank Mockenhaupt (Charité, Berlin, Germany)

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