Dr Matt Baker is a Lecturer in the School of Biotechnology and Biomolecular Sciences and an Affiliated Biophysicist at the EMBL Australia Node for Single Molecule Science at the University of New South Wales, in Sydney, Australia.
Matt completed his DPhil at Oxford University as a John Monash Scholar studying the bacterial flagellar motor that makes nearly all bacteria swim. Matt's recent work (Nat. Struct. & Mol. Biol 2016) demonstrated the novel domain-swap mechanism for rotor assembly, and he has focussed primarily on how simple subunit interactions govern assembly of complex architectures, including the filament (eLife 2017). The next question is how this complexity emerged. To begin addressing this, Matt's nascent group at UNSW looks at how ion selectivity changes using directed evolution to examine the evolutionary landscape that constrains the adaptation of the motor.