Teaching
BIOL 2121 Genes to Environment Lecturer
Research interests
- The control of root architecture in legumes.
- The identification of new angiogenesis therapeutics.
- The use of microalgae as a renewable energy source.
Current projects
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Control of Meristem Differentiation and Plant Architecture in Legumes
Plant Development is Controlled by New Regulatory Molecules
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Novel Small Molecule Regulators of Animal Development
Identification and characterisation of small plant-bioactive molecules that regulate mammalian development
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Chlamydomonas as a model system to optimise lipid production for biofuels
Optimising microalgae for biofuel production
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Student research opportunities
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Understanding the role of key regulators in determining root architecture
Investigating the role of genes that control root architecture
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Lab members
- Charles Buer (Research Fellow)
- Christina Delay (PhD student)
- Michael Djordjevic (Lab Leader)
- Rod Eyles (PhD student)
- Nijat Imin (Research Fellow)
- Gabriel James (PhD student)
- Farzaneh Kordbacheh (PhD student)
- Nadiatul Akmal Mohd Radzman (PhD student)
- Marie Oakes (Senior Technical Officer)
- Ann Wilks (School Visitor)
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Collaborations
Collaborations have been established with the following laboratories: - Other members of the ARC Centre of Excellence for Integrative Legume Research: Prof. Parish (JCSMR) and Prof Gresshoff (University of Queensland) and Dr. Mathesius and Dr. Weiller in RSB.
- Professor David Bird (Center for the Biology of Nematode Parasitism, North Carolina State University).
- Prof. Michael Udvardi (The Samuel Roberts Noble Foundation, Oklahoma).
- Assoc. Prof. Keith Lovegrove (ANU College of Engineering and Computer Science) and Assoc. Prof Dean Price and Dr. Warwick Hillier (RSB).
- Professor Lew Mander, Research School of Chemistry
- Prof. Dr. Wei-Dong Zhang, (Laboratory of Natural Products, Second Military Medical University, Shanghai).
- Dr. Oliver Yu (The Donald Danforth Plant Science Centre, Missouri)
- Dr Sasi Nayar, Dr Rod Thomas (SARDI, South Australia) and Professor David Levin (University of Manitoba, Canada)
Lab awards and achievements
- New components of regulatory networks that control the numbers of root nodules formed on Medicago have been identified.
- Methodologies for isolating variant Chlamydomonas strains that accumulate high levels of neutral lipids have been devised [James et al. 2010 Fatty Acid Profiling of Chlamydomonas reinhardtii under Nitrogen Deprivation. Bioresource Technology (in press)].
- Key genes involved in the induction of in vitro somatic embryogenesis and root formation in Medicago truncatula have been identified (Holmes et al. 2010. Global gene expression analysis of in vitro root formation in Medicago truncatula. Functional Plant Biology, 2010, 37, 1117–1131).
- Flavonoids act as long-distance plnat development signals and modulators of plant architecture (Buer et al. 2010. Flavonoids: New Roles for Old Molecules. Journal of Integrative Biology. 52: 98–111).
- Plant bioactive molecules (Nod factors and secondary plant metabolites) have been shown to modulate in vitro angiogenesis in rodent and human model systems in a concentration-dependent fashion.
- Extracellular endo- and exo-proteases have been identified that process CLE pro-peptides to biologically active peptide hormone products of different sizes and biological potency.
- A new classificiation system for Hox proteins has been proposed (Hueber et al. 2010. Improving Hox Protein Classification across the Major Model Organisms. PLOS ONE 5: e10820)
- The use of microalgal biomass as a source of renewable energy is being investigated via the BioSolar Project (a cross campus collaboration between biologists and engineers).
- As part of the BIOL2121 teaching team, Dr. Michael Djordjevic was awarded the Vice Chancellor's Excellence in Teaching Award (2010).
Publications
Selected publications
Buer, CS, Muday GK and Djordjevic, M.A. (2007). Flavonoids are differentially taken up, converted to downstream products, and transported long distances in Arabidopsis. Plant Physiology. 145 : 478-490.
Miyahara A, Hirani TA, Oakes M Kereszt A, Kobe B, Djordjevic M A., Gresshoff PM. (2008) Soybean nodule autoregulation receptor kinase phosphorylates two kinase-associated protein phosphatases in vitro. Journal of Biological Chemistry: 283: 25381-253
Djordjevic M.A., Chen H-C, Natera, SHA, van Noorden G., Menzel, C, Taylor, S., Geiger O, Weiller, G. (2003). A global analysis of protein expression profiles in Sinorhizobium meliloti: Discovery of new genes for nodule occupancy and stress adaptation. Molecular Plant-Microbe Interactions.16: 508-524.
Natera, S. H. A., Guerreiro N., Djordjevic, M. A. (2000). Proteome analysis of differentially displayed proteins as a tool for the investigation of symbiosis. Molecular Plant-Microbe Interactions, 13, 995-1009.
Mathesius U, Schlaman HRM, Spaink HP, Sautter C, Rolfe BG and Djordjevic MA (1998) Auxin transport inhibition precedes nodule initiation in white clover roots and is regulated by flavonoids and derivatives of chitin oligosaccharides. Plant Journal. 14: 23-34
Recent Publications
Djordjevic M.A., Oakes M.., Hocart C., Li, D. and Gresshoff, P.M. (2007). Analysis of secreted proteins present in Glycine max xylem sap. Journal of Proteome Research. 6: 3771-3779.
Buer CS, Djordjevic MA. (2009) Architectural phenotypes in the transparent testa mutants of Arabidopsis thaliana. J Experimental Botany 60 : 751-763.
Hueber SD, Weiller GF, Djordjevic MA, Frickey T. (2010). Improving Hox Protein Classification across the Major Model Organisms. PLOS ONE 5: e10820
Holmes P., Djordjevic M A. and Imin N (2010) Global gene expression analysis of in vitro root formation in Medicago truncatula. Functional Plant Biology. 2010, 37, 1117–1131.
James G.O., Hocart CH, Hillier W., Chen, H., Kordbacheh F., Price D and Djordjevic MA. (2010) Fatty Acid Profiling of Chlamydomonas reinhardtii under Nitrogen Deprivation. Bioresearch Biotechnology. doi: 10.1016/j.biortech.2010.11.051
All publications
Click here to see a full list of publications on the ISI website...
Recent grants
2008-2010 CEO348212 ARC Centre of Excellence for Intergative Legume Research
2009 Proof-of-concept grant ANU Connect Ventures. Synthesis of Nod factor variants that regulate mammalian angiogenesis.
2010-12 DP1096299 Dr MA Djordjevic; Prof LN Mander; Prof CR Parish New functions for bioactive flavonoids in plants and mammals.
2010 Optimising Lipid Yields in Microalgae for Next Generation Biofuels SA-Manitoba Bilateral agreement
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