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Professor Jennifer Graves

Building 46,
Research School of Biology,
The Australian National University,
Acton, ACT 0200
T: 61203 9439 5109
E: jenny.graves@anu.edu.au

 Biography:

Jenny is a Professor Emeritus at ANU. She no longer leads a lab at this University, but works in close collaboration with the laboratories of Dr Janine Deakin and Dr Paul Waters.

She has returned to Melbourne, where her primary position is:

Distinguished Professor
La Trobe Institute of Molecular Science
La Trobe University
Melbourne, VIC 3086

Teaching

Occasional guest speaker.

Research interests

Jenny's research focusses on the understanding of mammalian genome organization and evolution, exploiting the genetic diversity of Australia's unique mammals as a source of genetic variation to study highly conserved genetic structures and processes. This strategy is used to shed light on the organization, function and evolution of mammalian genomes, leading to new theories of the origin and evolution of human sex chromosomes and sex determining genes. Early work made classic contributions to our understanding of the molecular mechanism of X chromosome inactivation and the control of DNA synthesis in mammalian cells.

Current projects

Evolution of the Y chromosome

Characterising the marsupial Y        Show more detail...

Monotreme dosage compensation

Epigenetic regulation of the platypus X chromosomes        Show more detail...

Student research opportunities

Jennifer Graves is no longer taking students.

Lab members

Publications

Selected publications

1. Title: The promise of comparative genomics in mammals
Author(s): O'BRIEN, SJ; MENOTTI-RAYMOND, M; MURPHY, WJ; et al.
Source: SCIENCE Volume: 286 Issue: 5439 Pages: 458-+ Published: OCT 15 1999
Times Cited: 305

2. Title: THE ORIGIN AND FUNCTION OF THE MAMMALIAN Y-CHROMOSOME AND Y-BORNE GENES - AN EVOLVING UNDERSTANDING
Author(s): GRAVES, JAM
Source: BIOESSAYS Volume: 17 Issue: 4 Pages: 311-320 Published: APR 1995
Times Cited: 252

3. Title: Undermethylation associated with retroelement activation and chromosome remodelling in an interspecific mammalian hybrid
Author(s): O'NEILL, RJW; O'NEILL, MJ; GRAVES, JAM
Source: NATURE Volume: 393 Issue: 6680 Pages: 68-72 Published: MAY 7 1998
Times Cited: 200

4. Title: Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences
Author(s): MIKKELSEN, TS; WAKEFIELD, MJ; AKEN, B; et al.
Source: NATURE Volume: 447 Issue: 7141 Pages: 167-U1 Published: MAY 10 2007
Times Cited: 183

5. Title: SEX CHROMOSOMES DYNAMICS AND Y CHROMOSOME DEGENERATION
Author(s): GRAVES, JAM
Source: CELL Volume: 124 Pages: 901-914 Published: 2006 
Times Cited: 104

6. Title: EVOLUTION OF SEX DETERMINATION AND THE Y-CHROMOSOME - SRY-RELATED SEQUENCES IN MARSUPIALS
Author(s): FOSTER, JW; BRENNAN, FE; HAMPIKIAN, GK; et al.
Source: NATURE Volume: 359 Issue: 6395 Pages: 531-533 Published: OCT 8 1992
Times Cited: 150

7. Title: AN SRY-RELATED SEQUENCE ON THE MARSUPIAL X-CHROMOSOME - IMPLICATIONS FOR THE EVOLUTION OF THE MAMMALIAN TESTISDETERMINING GENE
Author(s): FOSTER, JW; GRAVES, JAM
Source: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume: 91 Issue: 5 Pages: 1927-1931 Published: MAR 1 1994
Times Cited: 146

8. Title: Genome analysis of the platypus reveals unique signatures of evolution
Author(s): WARREN, WC; HILLIER, LW; GRAVES, JAM; et al.
Source: NATURE Volume: 453 Issue: 7192 Pages: 175-U1 Published: MAY 8 2008
Times Cited: 146

9. Title: SEQUENCES HOMOLOGOUS TO ZFY, A CANDIDATE HUMAN SEX-DETERMINING GENE, ARE AUTOSOMAL IN MARSUPIALS
Author(s): SINCLAIR, AH; FOSTER, JW; SPENCER, JA; et al.
Source: NATURE Volume: 336 Issue: 6201 Pages: 780-783 Published: DEC 22 1988
Times Cited: 135

10. Title: Comparative painting reveals strong chromosome homology over 80 million years of bird evolution
Author(s): SHETTY, S; GRIFFIN, DK; GRAVES, JAM
Source: CHROMOSOME RESEARCH Volume: 7 Issue: 4 Pages: 289-295 Published: JUN 1999
Times Cited: 129

All publications

Click here to see a full list of publications on the ISI website...

Links




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