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Research projects

Mechanisms by which a chromatin-modifying gene targets gene expression and promotes memory

Epignetics is a memory forming process in plants that involves chromatin modifications. This proposal will unravel the regulatory mechanisms controlling carotenoid composition and epigenetic events in plants.        Show more detail...

Identification of novel carotenoid-derived signalling pathways affecting plant development

Carotenoids are colourful plant pigments. This proposal aims to identify new carotenoid signaling pathways regulating development in response to environmental change.        Show more detail...

The molecular nature of metabolic feedback regulation by metabolite-binding RNA riboswitches

Metabolite binding RNA riboswitches are rare in plants. This proposal will invesigate a putative metabolite-binding riboswitch in Arabidopsis.        Show more detail...

Regulation of carotenoid composition, growth habit and root-mycorrhizal symbiosis in tomato

Carotenoids play important roles in mediating root-mycorrhizal symbiosis as well as defining growth habit and development. This proposal will investigate how perturbing carotenoid compositon in tomato affects such processes.        Show more detail...

Carotenoids and Plant Development

This proposal will unravel the regulatory mechanisms controlling carotenoid composition as well as plant growth.        Show more detail...

Molecular virology

Characterising the genes of the Vaccinia virus        Show more detail...

Immunodominance in CD8+ T cell responses to vaccinia virus

Understanding and manipulating CD8+ T cell responses to viruses and genetically engineered virus vaccines        Show more detail...

Understanding how host genes affect anti-viral immunity

A study of the outcome of vaccination or virus infection in mice with mutations that affect anti-viral responses        Show more detail...

Understanding how environmental gradients impact on plant performance

A wide range of student opportunities are available in the area of environmental plant physiology/physiological ecology, including those listed under 'Current Projects'. Please email Owen.Atkin@anu.edu.au for further details.        Show more detail...

Role of poisonous plants in the foraging ecology of marsupials

Most of the plants that browsing mammals eat contain a complex series of natural toxins. How do these influence the plants animals choose to eat?        Show more detail...

Genetics and evolution of variation in chemical defence against herbivores

Why are some trees defended against herbivores and others not? Even when they grow right next to each other? Is it because of variations in soils or are genetic factors more important?        Show more detail...

How do animals learn about poisonous plants?

Animals don't forage randomly and have to make decisions continuously about nutrients and toxins in their food. How do they make decisions when the environment is so variable and when they also have to consider predators and social interactions?        Show more detail...

Viruses and immunity

Enquiries from prospective students with enthusiasm for immunology or virology are welcome.        Show more detail...

Asexual Sporulation in Stagonospora nodorum

To understand the molecular mechanisms of asexual sporulation in the pathogen Stagonospora nodorum        Show more detail...

Genetics of thyroid disease

Investigating the genetics of thyroid disease in the Canberra region        Show more detail...

Investigating the genetics of obesity

Using the Aussie Normal collection of genotype and phenotype information, investigating genes involved in obesity. This project is in collaboration with staff at JCSMR.        Show more detail...

Investigating the genetics of cardiovascular disease

Using the "Aussie Normal" collection genotype and phenotype investigations of markers of cardiovascular disease.        Show more detail...

Effector proteins in necrotrophic wheat pathogens

Effector proteins cause disease! How do they do it?        Show more detail...

Understanding the role and identifying targets of signal transduction in Stagonospora nodorum

What are the targets of signal transduction in fungal pathogens?        Show more detail...

Ion regulation in the malaria parasite

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Drug resistance and drug susceptibility in the malaria parasite

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Metabolism and metabolomics of the malaria parasite

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The biochemistry, physiology and pharmacology of the malaria parasite

Enquiries from prospective students are welcome.        Show more detail...

Research Projects (BIOL3174 or BIOL3175)

Interested in undertaking a research project to gain experience of common methodologies used in biochemistry and molecular biology?        Show more detail...

Biotechnology Research Proposal (BIOL8703)

Projects covering epigenetics, miRNAs, seed development and plant development are available.        Show more detail...

Summer Research Projects 2012/2013

Through this project, you will gain knowledge and experience of common methodologies used in molecular biology.        Show more detail...

Honours Research Project 2012 or 2013

Interested in joining our lab to undertake your honours project?        Show more detail...

RNA silencing and heritable epigenetic changes

The aim of this project is to investigate the extent of trans-generational effects of endogenous small RNAs in the model plant Arabidopsis.        Show more detail...

What molecular components are required for cell-to-cell movement of RNA silencing?

The aim of this project is to investigate the molecular components required for cell-to-cell movement of RNA silencing in the model plant Arabidopsis.        Show more detail...

Does RNA silencing contribute to seed size and hybrid incompatibility?

The aim of this project is to investigate the extent that seed size and endosperm development is determine by small RNAs in the model plant Arabidopsis.        Show more detail...

Honours, Masters and PhD projects available in fungal phytopathology

All current projects in the Solomon lab are available as Honours, Masters and PhD research projects        Show more detail...

Assaying Zic5 function in the developing mouse brain

This project focuses specifically on a condition called microcephaly, a neuro-developmental disorder in which a forebrain of normal architecture but reduced size is generated in utero.        Show more detail...

An improved Zic trans-activation assay

The aim of this project is to construct a more sensitive trans-activation assay to enable discrimination between Zic family members with respect to their ability to trans-activate the reporter.        Show more detail...

A new gene involved in mammalian axis formation

One aim of the project is to identify the mutated gene responsible for axis duplication. The second aim of the project is to characterize the phenotype of embryos that are homozygous for the mutation.        Show more detail...

Identification and characterisation of genes that are required for mammalian embryonic development

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The colon environment as a determinant of E. coli diversity

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Host social structure and the clonal composition of bacterial populations

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Subcellular localisation of plant disease resistance proteins

We have used green fluorescent protein fusions to localise flax resistance proteins conferring resistance to flax rust.        Show more detail...

Activation of plant disease resistance proteins

We have used site-directed mutagenesis and agroinfiltration to investigate molecular function in the tomato Cf-9 protein conferring leaf mould resistance.        Show more detail...

Identification and functional characterisation of flax rust Avr genes

This project will combine next generation sequencing, bioinformatics and classical genetics to identify new Avr genes, and use an array of molecular and cell biology techniques to analyse Avr gene function.        Show more detail...

Mapping and functional characterisation of the tomato I-7 gene for resistance to Fusarium wilt

This project aims to characterise I-7 resistance by microscopic analysis and digital gene expression analysis. We also aim to map I-7 and develop PCR-based markers for marker-assisted breeding of I-7.        Show more detail...

Identification and functional characterisation of the tomato I-3 gene for resistance to Fusarium wilt.

This project aims to identify the I-3 gene and to characterise the I-3 protein. We also aim to characterise I-3 resistance by microscopic analysis and digital gene expression analysis.        Show more detail...

The Zic genes and congenital defects

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Multifocal visual evoked potentials

measuring electrical responses of the visual system to many stimuli at the same time        Show more detail...

Multifocal pupillographic objective perimetry

similar to multifocal VEPs but where visual brain responses are recorded by video records of motions of the pupils        Show more detail...

Higher order image statistics and image texture

What is image structure, how do we compute it? How does our brain use it?        Show more detail...

The spatial frequency doubling illusion

When pushed the visual system responds in an odd way creating illusory percepts of textural fineness. We want to study the neural basis of these effects.        Show more detail...

Rates of molecular evolution in parasites

A broad comparative study using analysis of DNA sequence data from a wide range of parasites and their non-parasitic relatives        Show more detail...

Evolution of salt tolerance in plants

A biodiversity-based approach, using analysis of large-scale molecular phylogenies to understand adaptation to challenging environments        Show more detail...

Evolution of scald and net form of net blotch

Evolution of cereal pathogens        Show more detail...

Speciation in co-evolved taxa: sexually-deceptive orchids and their mycorrhizal symbionts.

Speciation processes in mycorrhizae and orchids        Show more detail...

Fungal bioinformatics

Identifying genes associated with mycorrhizae        Show more detail...

Ascochyta blight of chickpea

Population structure of A. rabiei        Show more detail...

Environmental risk assessment of genetically modified Alfalfa mosaic virus resistant white clover (Trifolium repens L.)

Risk assessment of AMV resistant clover        Show more detail...

Australian native truffle diversity

Australian native truffle diversity        Show more detail...

Factors affecting Perigord truffle production in Australia

Factors affecting Perigord truffle production in Australia        Show more detail...

Pest resistance and sustainable plantation management of eucalypts

Insect and vertebrate herbivores represent an important cost to eucalypt forestry. Our work aims assess the potential for breeding resistant trees in order to improve the viability of plantations especially in farm forestry.        Show more detail...

Ecology, genetics and physiology of animal-plant interactions

Enquires from prospective students are welcome in any of the areas described above.        Show more detail...

Nutrition of free-ranging primates

How do primates make a living in natural forests when nutrients are either poorly available or sparsely distributed?        Show more detail...

Diseases of amino acid transport

Disorders of epithelial transport affecting intestinal and renal transport        Show more detail...

Amino acid transporters as signalling molecules

Transporters are involved in metabolite uptake and signalling processes        Show more detail...

Amino acid transporters as ion channels

Transporter and channels are related, some proteins have both functions        Show more detail...

From Animal to Robots and Back

We investigate the knowledge-base of detouring and goal-directed navigation in insects        Show more detail...

Visual Information Processing under Natural Conditions

Combining field work on crab behaviour with electrophysiological and optical techniques, this projects aims to understand how fiddler crabs use visual information to organise their anti-predator behaviour under natural conditions.        Show more detail...

Colour Vision in Australian Marsupials

Marsupials are the only non-primate mammals with trichromatic colour vision. This project aims to understand the diversity and mechanisms of their colour vision using behavioural, anatomical and physiological techniques.        Show more detail...

Alarm signals and interspecific eavesdropping

We test ideas about the information encoded in alarm calls and used by others of the same and different species        Show more detail...

Parent-offspring communication under the risk of predation

We are interested in how acoustic communication between parents and their offspring is shaped by the risk of predation        Show more detail...

Vocal mimicry

We study the acoustic accuracy, context and possible functions of avian vocal mimicry        Show more detail...

Acoustic communication in birds

Most of my students study acoustic communication in birds        Show more detail...

Regulation of cricket salivary glands

Examines the way that feeding affects the morphology and chemistry of the insect salivary gland.        Show more detail...

Feeding and ecology of grapevine scales

The phenology and ecology of grapevine scales in the region around the ACT are being studied to understand the reason these insects are a problem to the wine industry.        Show more detail...

Regulation of rat reproduction in rice fields of south east Asia

Natural chemicals are being screened to determine how rat reproduction may be controlled in the rice fields.        Show more detail...

Biological adaptation under natural and anthropogenic conditions

Combining mathematical and empirical work to understand what (if anything) is optimized by evolution across various levels of biological organization.        Show more detail...

From Molecules to Memory

To understand how long-term memories are stored in the brain. Model organism: social bees.        Show more detail...

Epigenetic integration of genomic and environmental information in honey bees

To study the link between DNA methylation and environmental influences.        Show more detail...

How DNA-methylation contributes to long-term memory

To examine changes in the epigenome associated with the consolidation of long-term memory        Show more detail...

Eco-evolutionary feedbacks

Investigating the rules of the "evolutionary play in the ecological theatre"        Show more detail...

Epigenomics of brain wiring and behaviour in honey bees

To study epigenetic profiles of neuronal cell types in the honey bee brain        Show more detail...

Tracking the evolution of devil facial tumour disease

Characterisation of normal and tumour genomes at the cytogenetic level        Show more detail...

Duetting and female song in Australian passerines

Several projects are available to explore the social and ecological conditions that select for song in female birds        Show more detail...

Out of the darkness: predicting rates of respiration of illuminated leaves along nutrient gradients

This project seeks to establish whether there are systematic differences in light inhibition among species, and how phosphorus limitations and diurnal variations in temperature impact on leaf respiration.        Show more detail...

The evolution of mouth markings in estrildid finches

The aim of this project is to test whether the bright mouth markings of estrildid finches have evolved to provide a means of discriminating brood parasitic chicks in the nest        Show more detail...

Leaf respiration under drought: a global perspective

We are combining laboratory and field experiments to establish whether there are systematic differences among species in drought-mediated changes in respiration, and how drought impacts on the temperature dependence of respiration        Show more detail...

Establishing a process-based understanding of the impacts of climate change on plant respiration

Our aim is to establish a process-based understanding of mitochondrial and intact tissue respiratory responses to drought and global warming scenarios        Show more detail...

Role of alanine aminotransferase in improved nitrogen use efficiency in cereals

This project is defining the phenotype of transgenic crop plants that have improved nitrogen use efficiency        Show more detail...

Co-evolution between Australian cuckoos and their hosts

A range of projects are available to explore the tactics deployed by cuckoos to fool their hosts, and the reciprocal strategies that have evolved in hosts to defend themselves against brood parasites        Show more detail...

Structural and functional analysis of glucosyl and O-acetyl transferases of Shigella flexneri

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The role of N-terminal post-translational modifications of the tobacco Rubisco large subunit

Understanding the role and function of post translational protein modifications in chloroplasts using the model protein Rubisco        Show more detail...

Dendritic cell biology

Characterisation of a novel antigen presenting cell        Show more detail...

Environmental physiology of locusts

Temperature regulation and acclimation of locusts to high and low temperatures. Reproductive physiology of locusts.        Show more detail...

Studies on the biochemical regulation of C3 and C4 photosynthesis

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CO2 diffusion inside leaves

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Insect ecology, morphology or physiology

Any topic that encompasses some aspect of insect feeding biology or morphology will be supported.        Show more detail...

Stem Cell Niches

The endothelial cell microenvironment in spleen        Show more detail...

Stem Cells in Immunology

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Extramedullary Hematopoiesis

Spleen as a site for myelopoiesis        Show more detail...

Transcriptome and genome sequencing of the coral, Acropora millepora.

Our goal is to achieve transcriptome and genome sequence databases that are as complete as possible.        Show more detail...

Expression of modified tobacco and foreign Rubiscos in tobacco chloroplasts

Examining how plant photosynthesis and growth is influenced by transplanting foriegn or modified Rubisco into higher plant chloroplasts        Show more detail...

Diversification and macroevolution of Proteaceae

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Rarity and extinction risk in the southwest Australian flora

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Diversity and coexistence in southwest Australian plant assemblages

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Diversity and macroecology of island mammals

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Global patterns of biodiversity

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Organic components of the coral skeleton

Organic components of the coral skeleton We are using mass spectrometry, in conjunction with our nearly complete transcriptome, to identify organic components of the coral skeleton.        Show more detail...

Comparative genomics and development of corals

High throughput sequencing, combined with in situ hybridization, allows us to investigate how homologous genes are expressed in animals of quite different morphologies during development.        Show more detail...

Biophysical coupling in coral reef ecosystems

Unravelling how physio-chemical gradients influence coral reef ecosystem processes over space and time.        Show more detail...

Adaptive swimming behaviour in coral reef fishes

Behavioural flexibility as a means of adaptation to a rapidly changing environment.        Show more detail...

Development of the coral nervous system and its role in metamorphosis

The availability of transcriptome data allows us to take new approaches in our studies of the structure and function of the coral nervous system.        Show more detail...

The molecular basis of coral biology

Enquiries from prospective students and post-docs are welcome.        Show more detail...

Student research projects in CO2 fixation and water loss of leaves

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Microbial control of root developmental plasticity

The aim of this project is to identify mechanisms that link microbial signals with changes in root development.        Show more detail...

The role of flavonoids in root-microbe symbioses and root development

The aim of this project is to understand the molecular mechanisms of plant flavonoids in root-bacterial and root-nematode interactions.        Show more detail...

Environmental regulation of root symbioses

The aim of this project is to find out how changes in the environment interfere with the success of nitrogen fixing symbioses.        Show more detail...

Rhizosphere signalling

The aim of this project is to find out how microbial signals from the rhizosphere alter root symbioses and root development        Show more detail...

The evolution of genital size in mosquitofish

Why do genitalia show such a precise allometric relationship with body size in these fish?        Show more detail...

Examining Rubisco - Rubisco activase interactions.

Genetic, biochemical and physiological tools are being used to explore which residues in Rubisco and its chiropractic helper protein, Rubisco activase, that influence their interactions        Show more detail...

The Directed evolution of RuBisCO

The powerful protein engineering tool of laboratory evolution is being applied to Rubisco        Show more detail...

Exploring the evolutionary protein landscape of Rubisco

Projects are available that aim to exploit, and upgrade, our novel Rubisco evolution screening systems        Show more detail...

Overcoming limitations in engineering the Rubisco small subunits in higher plant chloroplasts.

Strategies for efficiently engineering the small subunit of higher plant Rubisco are being developed        Show more detail...

Supercharging CO2-fixation by plants

Projects are availble aimed at discovering fundamental issues relating to Rubisco biogenesis, its manipulation in chloroplasts and influence of photosynthetic C-assimilation and plant growth.        Show more detail...

Unravelling novel Rubisco structures in algae.

Many of the algae forming symbiotic associations with coral reef organisms have unique forms of Rubisco which we know very little about        Show more detail...

Dissecting Rubisco catalysis in C3 and C4 plants

We hope to understand what structural features make the Rubisco from C4 plants faster and integrate this feature into the slower Rubisco in C3 plants        Show more detail...

Scrutinizing the influence of temperature on Rubisco catalysis.

Improving our appreciation of how Rubisco catalysis is affected by higher temperatures is paramount towards understanding how ecosystem producitivty will be affected by climate change        Show more detail...

Student opportunites in the phenomic analysis of CO2 acquisition by cyanobacteria

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Student opportunities in molecular analysis of CO2 acquisition by cyanobacteria

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Physiological and molecular regulation of stomatal movement

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Genes, diet and environment

To understand how the outside world is linked to DNA        Show more detail...

Sexual selection in the field cricket Teleogryllus commodus

We are exploring a range of question relating to male singing behaviour, female mate choice, sperm competition, immunocompetence and diet.        Show more detail...

CO2 acquisition by cyanobacteria and plants, and impact of climate change

Projects deal with CO2 acquisition by cyanobacteria and plants, and impact of climate change, and engineering plants that use less water        Show more detail...

Sexual Selection and the Evolution of Sex Roles

I am open to students proposing studies - be they meta-analyses (I can teach you the techniques), empirical work (as long as we have lab space or there is a suitable field site) or theoretical studies.        Show more detail...

Have bacteria hijacked plant developmental pathways?

We are investigating how bacteria have evolved to alter induce new root organs by interfering with planthormones.        Show more detail...

Combatting plant parasitic nematodes

We are investigating the use of RNA interference technology to prevent plants from being devastated by root knot nematodes.        Show more detail...

Can plants intercept bacterial small-talk?

We are investigating whether the detection of bacterial quorum sensing signals by plants helps them combatting bacterial infection.        Show more detail...

Co-evolution between Australian cuckoos and their hosts

An investigation of the co-evolutionary arms races between Australian cuckoos and their hosts        Show more detail...

The impact of climate change on inter-specific interactions

An investigation of the phenological mismatch hypothesis for interactions between cuckoos, their hosts and their prey in south-eastern Australia        Show more detail...

The evolution of song in female birds

Female birdsong is unusual in the northern hemisphere, so why do females of so many Australian species sing?        Show more detail...

Distinguishing among patterns of extinction and speciation through geological and climatic change

This study will develop a new view of how the diversity of life has evolved across vast periods of time by using and improving new statistical molecular modelling tools.        Show more detail...

Effects of photobiomodulation on retinal trauma

Treatment with NIR light following retinal trauma.        Show more detail...

Fiddler Crabs: sex, territoriality and beyond

I conduct research on a wide range of questions related to the mating and social behaviour of fiddler crabs.        Show more detail...

Fiddler crabs: Current Projects

My students and I are currently conducting research on a wide range of topics related to the behaviour of fiddler crabs        Show more detail...

Protective effect of photobiomodulation on the degenerative retina

NIR light treatment will be used to protect degenerative retinae from damage caused by excessive light        Show more detail...

Student research projects in tumour immunology and liposome targeting

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Student opportunites in molecular plant-microbe interactions

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Genotypic variation in Rubisco between diverse wheats

Rubisco varies between wheat species and we are seeking to relate different forms of Rubisco to photosynthetic performance in the leaf        Show more detail...

Photosynthesis, food security and global change

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The sensing and signalling of mechanical stress by roots- Genetic regulation of root:shoot communication and function under drought

Roots as environmental sensors and signalling agents to aerial meristems, expanding leaves and stomata.        Show more detail...

Phytophthora pathogenicity

Phytophthora species are fungus-like plant pathogens that cause destructive diseases in important crop plants worldwide        Show more detail...

Infection of plants by rust fungi

Fungal pathogens secrete effector proteins that are transported into the cytoplasm of host plant cells        Show more detail...

Transpiration efficiency genes. Manipulating the coordination of CO2 fixation and water loss in leaves-

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The role of phospholipids and lipid signalling in the plasticity of growth and development

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Coordination of cellular growth and proliferation. Development, patterns and morphogenesis.

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Inhibiting innate immunity to prevent retinal degeneration

The innate immune response, specifically the complement system plays and important role in the progression of retinal degenerations, including AMD. In this project we trial a novel complement inhibitor in models of retinal degeneration        Show more detail...

Dietary supplements in the prevention of retinal degeneration

Dietary supplements, especially natural products recently have become more prominent in biological research and their use in therapies is becoming more common. We are investigating their role in retinal degenerations.        Show more detail...

Protective effect of photobiomodulation on light-induced retinal degeneration

Using NIR light to prevent or repair damage caused by bright light in the retina.        Show more detail...

Phytophthora zoospore motility

Motile spores facilitate plant infection        Show more detail...

Phytophthora zoospore adhesion

Rapid secretion of adhesives attaches pathogen spores to the surface of potential hosts        Show more detail...

Phytophthora cell wall degrading enzymes

Secretion of cell wall degrading enzymes are responsible for plant penetration        Show more detail...

New Molecular Targets for Drugs to Treat Human and Animal Nematode Parasites

Functional genomics of C. elegans to identify and validate new antinematode drug targets.        Show more detail...

Fungal effector uptake into plant cells

Pathogens secrete effector proteins that are transported into the cytoplasm of infected plant cells        Show more detail...

New Control Methods for Plant-parasitic Nematodes

Investigating the use of RNA interference to control plant-parasitic nematodes.        Show more detail...

Olfactory Pattern Recognition in Nematodes

An investigation of olfactory receptors in C. elegans        Show more detail...

Olfactory receptors in C. elegans

Identifying potential olfactory receptors in C. elegans.        Show more detail...

Shigella virulence and vaccine development

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Functional genomics of serotype-converting bacteriophages of Shigella flexneri

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Student research projects in plant development, root:shoot communication and drought signalling

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Australian Alpine Seed and Seedling Ecology

This ARC linkage project examines the seed and seedling ecology of Alpine plants with an aim to conseration and management under climate change        Show more detail...

The evolution and functional sigificance of leaf shape

This project asks why leaf shapes vary and how do diverse leaf shapes evolve.        Show more detail...

Evolution of the Y chromosome

Characterising the marsupial Y        Show more detail...

Monotreme dosage compensation

Epigenetic regulation of the platypus X chromosomes        Show more detail...

Marsupial X chromosome inactivation

Discovering the epigenetic signature associated with the inactive X in marsupials        Show more detail...

Investigating immunomodulatory treatments for severe influenza

This project looks at damping parts of the host immune response to influenza virus, so as to reduce morbidity and mortality.        Show more detail...

Vitamin utilisation by malaria parasites

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Investigating the interactions between respiration and photosynthesis in leaf photosynthetic function.

Aim: Gain a greater understanding of the interactions between mitochondrial respiration and photosynthesis using targeted Arabidopsis respiration mutants.        Show more detail...

Characterization of low and high CO2 sensitive Arabidopsis photosynthetic mutants

Aim: To understand the function of previously unknown genes in the ability of photosynthesis to function under either low or high CO2 conditions.        Show more detail...

Chromosomal evolution in the Social huntsman spider Delena cancerides.

Understanding chromosomal evolution and its role in the speciation process        Show more detail...

Evolution of the Australian Onychophora

Morphological, chromosomal and behavioural diversification in the Australian velvet worms ("Peripatus).        Show more detail...

Pathways of photosynthetic electron flow under environmental stress

We track the light-induced electron transfers in situ in leaves working under defined environmental conditions.        Show more detail...

Dynamic architecture of plant thylakoid membranes between light and dark

The architecture of photosynthetic membranes is not static, but undergoes re-organisation on illumination. Elucidation of the re-organisation helps us to understand the relation between the structure and function of the membranes.        Show more detail...

Student projects in thylakoid function and structure

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Photoprotection and photoinactivation of Photosystem II

Light is both necessary for photosynthesis and harmful to the photosynthetic apparatus. This project investigates the photoprotection and photoinactivation of Photosystem II, and recovery from photoinactivation        Show more detail...

Entropy as a novel determinant of photosynthetic structure and function

In this project, we explore the photosynthetic apparatus as a system where light energy interacts with living matter, subject to thermodynamic constraints of which entropy has been seldom studied.        Show more detail...

Above and below-ground specialization in Australian orchids

This project is exploring the consequences of pollinator and fungal interactions for orchid speciation and vulnerability        Show more detail...

The chemical, biochemical, genetic and ecological basis of pollinator-driven speciation in Australian orchids

This project explores the critical role of pollinators in plant evolution and speciation        Show more detail...

Limiting factors and impacts of climate change for endangered Australian orchids

This project is assessing the role of multiple factors limiting endangered orchids        Show more detail...

Honeybee visual systems

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Control of Meristem Differentiation and Plant Architecture in Legumes

Plant Development is Controlled by New Regulatory Molecules        Show more detail...

Pigment Binding Proteins

Designing proteins for binding Pigment-Chromophores        Show more detail...

Molecular Biofuels

High Density Energy Storage        Show more detail...

Tree water use, bushfires, and the implications for urban and rural water supplies

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Theory and application of Maximum Entropy Production

Looking at what plants and ecosystems do from a thermodynamic perspective        Show more detail...

Photosynthetic Water Splitting

How Atmospheric Oxygen is Made        Show more detail...

Plant optimisation modelling

Optimisation models: new tools for global change science        Show more detail...

Oxygen and Water Channels in Proteins

Maximizing Chemical Reactions        Show more detail...

Artificial Photosynthesis

Engineering Model Photoactive Proteins        Show more detail...

pH regulation in the malaria parasite

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Herpes Simplex Virus and survival of infected cells

Investigating herpes simplex virus (HSV) latency and the role of the immune system in survival of infected cells        Show more detail...

Physics of pan evaporation

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Understanding chloroplast/nuclear signaling and response pathways which determine photosynthetic capacity

Aim: To gain new insights into chloroplast/nuclear signaling pathways using in mutants where normal protein expression is perturbed by RNAi down regulation.        Show more detail...

Understanding the cellular and genetic basis of differences in photosynthetic leaf capacity between Arabidopsis and a close mustard relative Hirschfeldia incana.

Aim: To use comparative analysis of Arabidopsis and a closely related mustard species, Hirchfeldia incana, to gain an understanding of what determines various aspects of leaf photosynthetic capacity and its environmental plasticity.        Show more detail...

Where physics and maths meet biology

Research challenges at the physics-maths-biology interface        Show more detail...

Coping with temperature extremes: morphological constraints on leaf function in a warmer, drier climate:

We are combining field and laboratory studies to determine how hydraulic traits of evergreen leaves affect their tolerance of temperature extremes with change in atmospheric CO2 concentrations.        Show more detail...

Entropy, information theory and biodiversity

New entropy-based tools for understanding ecological and genetic diversity        Show more detail...

Immunological protection of marsupial pouch young

Immune tissues in marsupials develop after birth, raising questions about how they survive in a potentially hostile environment.        Show more detail...

Salinity tolerance along an aridity gradient: linking physiological processes with morphological constraints on leaf function in mangroves

We are studying interrelationships between salinity tolerance and the functional coordination of plant hydraulics, leaf morphology and gas exchange characteristics in mangroves.        Show more detail...

Novel Small Molecule Regulators of Animal Development

Identification and characterisation of small plant-bioactive molecules that regulate mammalian development        Show more detail...

Climate change and carbon gain in Antarctic mosses

We are studying interspecific differences in thermal tolerance of Antarctic mosses in relation to climate warming.        Show more detail...

Ecophysiology of salinity and temperature tolerance in a changing world

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Chromosome condensation and T cell development

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Investigations into a possible therapeutic cancer vaccine.

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Identification of novel splice variants in the human and mouse genomes

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Structure and function of sulphate transporters

This project will involve investigation of function and interactions of sulphate transporters using mutagenesis, functional assays and yeast two hybrid approaches.        Show more detail...

Chloroplast development

The plant organelles responsible for the plants ability to perform photosynthesis, the chloroplasts, are essential for plant growth and vitality.        Show more detail...

Protein modification in chloroplast

A light sensitive mutant, snowy cotyledon 4, has been isolated with a mutation in a CAAX-proteinase function        Show more detail...

SCO Protein interaction partners

Several novel proteins have been identified in the mutant analysis of snowy cotyledon mutants, but mostly nothing is known about their function        Show more detail...

Gain of function mutants

In aim to unravel the regulatory network of chloroplast biogenesis second site mutants of snowy cotyledon 2 and snowy cotyledon 3 have been identified        Show more detail...

Student research opportunities in immunology

Projects investigating T-cell development, cancer vaccines and novel splice variants available in the Fahrer lab.        Show more detail...

Chlamydomonas as a model system to optimise lipid production for biofuels

Optimising microalgae for biofuel production        Show more detail...

Understanding the role of key regulators in determining root architecture

Investigating the role of genes that control root architecture        Show more detail...

Pigeon Foveal Development

Determine how the foveal location is specified during eye development        Show more detail...

OCT analysis of earlier changes in the central retina of AMD and glaucomatous maculae

Determine the normal and diseased parameters affecting visual acuity        Show more detail...

Retinal function of the aged fovea using pigeon as a model

Determine whether the function and cellular composition of the fovea changes with age        Show more detail...

non-coding RNA and micro RNA genes in plants

Identification and characterisation of non-coding RNA genes using a computational approach        Show more detail...

Analysis of gene expression

Developments of new methods for functional interpretation of gene epression data        Show more detail...

Organism specific sequence motifs

Development of a method of finding signiture sequences for for a phylogenetic group of organism        Show more detail...

Evolutionary biology of Australian reptiles and amphibians

Evolutionary biology of Australian reptiles and amphibians        Show more detail...

The Behavioural Ecology of Mosquitofish

We are interested in a range of question related to behavioural decisions and life history evolution in Gambusia.        Show more detail...

Drug resistance in the human malaria parasite

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Design and evaluation of novel antimalarial drugs

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Phototransduction and adaptation - the conversion of light into a neural signal

Our primary research interest is to elucidate the molecular mechanisms underlying phototransduction and adaptation - the conversion of light into a neural signal, and subsequent recovery, in retinal rod and cone photoreceptors and in bipolar cells.        Show more detail...

Characterisation of the microflora of Australian aeolian dust and its sources

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Microbiological Aspects of Crohn's Disease

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Microbial ecology of Lactobacillus strains in the chicken GIT: identification of persistent strains for use as live vectors

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Characterisation of the chicken gut microflora

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Identification and characterisation of membrane transport proteins

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Photoprotective functions of xanthophyll pigments in avocado

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Gene expression in the human macula

The central region of the retina is vulnerable to degeneration, especially associated with aging. In this study we hope to identify genes which predispose humans to macular degeneration.        Show more detail...

The Role of the immune system in photoreceptor degeneration

This project aims to identify the role that the immune system plays in the progression of retinal degeneration        Show more detail...

The effect of 670nm light irradiation on growth and development

Recent studies have shown that irradiation with 670nm light modulates expression of genes that regulate metabolism. In this study we aim to determine the effects of irradiation on new born rodents        Show more detail...

The effect of 670nm light irradiation on growth and development

The aims of the project is to determine the effect of irradiation with 670nm light on growth and development of major organs        Show more detail...

Development Aging and Degeneration of the Retina

Worldwide, loss of central vision is the major cause of impairment, untreatable blindness and poor quality of life. Projects in this lab are aimed at understanding aspects of development and aging that predispose the retina to degeneration.        Show more detail...

Issues raised by reproductive genetic technologies

Reproductive genetic technologies in Australia: regulation, communication and issues        Show more detail...

Impact of new technologies on humans and society

Project topics can be designed in collaboration with students. Please email me to make an appointment to discuss possible projects        Show more detail...

Ethics in science education

Project topics can be designed in collaboration with students. Please email me to make an appointment to discuss possible projects        Show more detail...

Sensory processing in the spinal cord

Sensory information reaches the brain regions via direct (purely conductive) or indirect (neuronal processing) spinal cord pathways. This project will measure the contribution of these different routes by which the spinal cord relays sensory information.        Show more detail...

Light therapy for neural regeneration

This project investigates the use of lasers for promoting regeneration after central and peripheral neural injury.        Show more detail...

Adult stem cells for central nervous system repair

Bone marrow cells can cross the blood brain barrier in response to central nervous system (CNS) injury.        Show more detail...

The bionic hand

This project will use computational methods to decode signals generated from the central nervous system to control a bionic hand.        Show more detail...

Cancer metabolism

Cancer cells use amino acid to generate energy. We are investigating amino acid transport and metabolism in cancer cells.        Show more detail...

Behavioral properties of the visual brain

We have shown that the visual system is an active structure in which the animal's actions and intentions alter the way that visual information is processed.        Show more detail...

Cortical development

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Visual prostheses

The so-called bionic eye is a device in which an array of stimulating electrodes is placed on the retina of a blind patient.        Show more detail...

Reading the isotopic archive: carbon and oxygen stable isotope ratios as recorders of plant physiological processes

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Honours and PhD student research in plant ecology and ecophysiology

Research opportunities in the lab can be tailored to the interests of PhD, Honours and Undergrad students in a wide range of topics, including each of the current projects above. Contact Adrienne (Adrienne.Nicotra@anu.edu.au) for more information.        Show more detail...

Phenotypic plasticity in plants: evolution, adaptation and its relevance in a changing climate

This research into plant responses to the novel environments posed by climate change will assess whether we can breed for more responsive crops or predict native plant tolerance of climate change.        Show more detail...

Population variation for seed and seedling traits along a gradient: assessing plant species persistence in South West Western Australia under a changing climate.

Examining the influence of projected climate change on seed and seedling traits in four seeder Banksia species in the South West Western Australia        Show more detail...

Biological requirement for miRNA regulation

To understand the conceptual requirement for miRNA regulation        Show more detail...

Elucidating the role of phenotypic plasticity and local adaptation in the evolution of Australian Pelargonium species

In this project we aim to assess phenotypic plasticity and local adaptation in water use traits of Australian Pelargonium species        Show more detail...

Ecophysiology of alpine dioecious species: Examining sexual dimorphisms under harsh conditions

This project is focused on ecophysiological differences between female and male plants that live at different altitudes in the alpine area of Mt. Kosciuszko, NSW.        Show more detail...

Responding to change: phenotypic plasticity and local adaptation, case studies using native and invasive Erodium spp

This project investigates phenotypic plasticity of an invasive and native Erodium to water availability using field collected seeds in a series of greenhouse experiments        Show more detail...

Ecology and evolution of Meconopsis Vig. (Papaveraceae) in Eastern Tibet

This project examines ecological factors underlying the distribution of various Meconopsis species in Eastern Tibet, their phylogeny and the evolution of their breeding systems        Show more detail...

The physiological and growth response of subtropical Eucalypts to defoliation

This project examines the response of sub-tropical Eucalypt species to repeated defoliation and water stress        Show more detail...

Hormosira banksii in high intertidal rockpools on Kainga Reef, Burrawarra Point, NSW

This project examines seasonal variation in growth of algal species along the NSW coast.        Show more detail...

Hormosira banksii in high intertidal rockpools on Kainga Reef, Burrawarra Point, NSW

This project examines seasonal variation in growth in rocky tidal algae on the NSW coast.        Show more detail...

Hormosira banksii in high intertidal rockpools on Kainga Reef, Burrawarra Point, NSW

This project examines seasonal variation in growth of rocky tidal algae on the NSW coast        Show more detail...

Dormancy and germination in Aciphylla glacialis, an alpine perennial

This project looks at whether seed dormancy in Aciphylla glacialis differs for seeds sourced from high and low altitudes in Kosciuszko National Park        Show more detail...

The use of nanofibres for nervous repair

This project will use nanofibres as a grafting material for treatment of spinal cord and peripheral nerve injury        Show more detail...

Understanding the mechanisms of thermal acclimation in the symbiotic algae (Symbiodinium) within cnidarian corals

Identify gene(s) associated with thermal acclimation mechanisms in symbiotic algae (Symbiodinium)        Show more detail...

Characterising the Mycosphaerella graminicola-wheat interaction

A primary biosecurity threat to the Australian wheat industry        Show more detail...

Summer scholarships in plant ecology and ecophysiology

This summer projects in the lab will include alpine ecology and reproductive biology as well as glasshouse projects on phenotypic plasticity in response to water availability. Contact Adrienne (Adrienne.Nicotra@anu.edu.au) for more information.        Show more detail...

Student research in stable isotopes and ecophysiology

Environmental plant biology        Show more detail...

Characterization of low CO2 sensitive Arabidopsis photosynthetic mutants

: To understand the function of previously unknown genes in the ability of photosynthesis to function under low CO2 conditions.        Show more detail...

Evolution of Vertebrate Sex Chromosomes and Dosage Compensation

Enquiries from prospective students are welcome        Show more detail...

Synthetic nanotubes to mimic biological ion channels

Synthetic nanotubes to mimic biological ion channels        Show more detail...

Membrane transport proteins of the malaria parasite and their roles in mediating drug resistance

Enquiries from prospective students are welcome.        Show more detail...

Marsupial genomics

Enquiries from prospective students are welcome for any of the above projects.        Show more detail...

The role of phospholipid flippases in the immune system

B-cell development requires a specific distribution of membrane phospholipids. Mutations in enzymes mediating phospholipid transport can cause immunodeficiency.        Show more detail...

Rust resistance in Australian Myrtaceae

The exotic plant pathogen myrtle rust has recently arrived in Australia with devastating effects for the environment and dependent industries.        Show more detail...

X inactivation in human placentae

In humans, the fetus employees sex specific growth strategies to cope with a stress (e.g.asthma) during pregnancy. Are these sex-specific differences related to differences in expression of genes on the X chromosome?        Show more detail...

Escherichia albertii: an avian and human pathogen

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Comparison of Escherichia coli in birds and humans

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E. coli within and among host dynamics in poultry

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Distribution of novel Escherichia species

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Role of gonadotrophins in the maintenance of reproductive quiescence of the female tammar wallaby.

Study aimed at understanding role of GnRH in maintenance of corpus luteum and/or blastocyst quiescence in tammar wallabies        Show more detail...

Effect of endocrine disruptors on reproduction in daphniids

Endocrine disruptors are chemicals produced by humans that can affect a number of hormonally controlled processes in other organisms. This study will examine how reproduction is affected by endocrine disruptors in the aquatic daphniids (Crustacea)        Show more detail...

Effects of hyperoxia and 670nm light on brain development in mice.

This project will examine the effects of 670nm light treatment on different regions of the brain.        Show more detail...

Effects 670nm light on oxygen-induced retinopathy in mice

This project aims to investigate a new treatment for retinopathy of prematurity        Show more detail...

Effect of 670 nm light on lung development

Newborn mice treated with red light grow faster than littermates, and their lungs weigh more. This project will examine lung development in treated mice and littermates        Show more detail...

Localization, and effects of inhibition, of macrophage chemoattractant molecules in the light-induced model of retinal degeneration.

Retinal degeneration is mediated by macrophages attracted into the retina by chemoattractant signals. How does modification of the chemoattractant signal effect progression of degeneration?        Show more detail...

Immune genes of the bearded dragon

Characterisation of the reptilian immune system is required to gain a greater understanding of the evolutionary history of the vertebrate immune system        Show more detail...

Avoiding coral bleaching

Investigation into the repair of damaged photosynthetic machinery in symbiotic algae (Symbiodinium) within corals        Show more detail...

Finding the oldest molecular fossils of cyanobacteria

1.64 billion years ago Cyanobacteria layed down Biomarkers into sediments        Show more detail...

Mycotoxin discovery and characterisation

What mycotoxins compounds do necrotrophic fungal pathogens of wheat produce and what is their role?        Show more detail...

New approaches to discovering biodiversity and understanding its response to climate change

New technologies will be used to predict and discover biodiversity hotspots in Australia, especially in the, as yet, poorly-known monsoonal tropics.        Show more detail...

Landscape Genomics

Population based genome sequencing across environmental samples        Show more detail...

Genome Wide Association Mapping

Determine the Genetic Architecture of Adaptive Traits in Plants        Show more detail...

Understanding novel epigenetic mechanisms using a model plant.

A research project suitable for an undergraduate research project or ASC.        Show more detail...

How does your garden grow? Scaling functional traits to whole-plant growth

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Will stomatal responses to humidity and carbon dioxide constrain tropical forest productivity as atmospheric carbon dioxide rises?

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Why does cancer chemotherapy fail?

Overcoming drug efflux pumps to restore sensitivity to anti-cancer drugs        Show more detail...

Lipid flipping in vision: seeing is believing!

Does aberrant phospholipid flip-flop underpin visual disorders?        Show more detail...

Starving tumours

Perturbation of metabolic changes in solid tumours to effect therapy        Show more detail...

Bioinformatic methods for epigenomic data analysis

The project involves the development of new methods to understand epigenetic regulatory mechanisms.        Show more detail...

Coral development and comparative genomics

Data from the transcriptomes and genomes of various corals are used to gain insight into genes and regulatory networks that underpin the development and physiology of corals.        Show more detail...

Erythrocyte membrane modifications during malaria infection

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Function of molecular chaperones in the export and display of parasite proteins

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Cellular adaptations that allow the transmission and survival of Plasmodium falciparum when taken up by the mosquito

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Molecular tools to reveal protein function and identify drug targets

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Apicoplast and mitochondrial metabolism in apicomplexan parasites

What are the metabolic functions of the apicoplast and mitochondrion in apicomplexan parasites?        Show more detail...

Apicoplast and mitochondrial biogenesis in apicomplexan parasites

How are the apicoplast and mitochondrion of apicomplexan parasites made?        Show more detail...

The unique cell biology of Toxoplasma gondii

What makes Toxo tick?        Show more detail...

Cell biology and metabolism of apicomplexan parasites

Enquiries from prospective students and researchers with an interest in cell biology, biochemistry, parastiology and/or evolution welcome!        Show more detail...

New antibiotics that target membrane channels

Designing peptides that interfere with bacterial ion channels to combat antibiotic resistance        Show more detail...

How do biological molecules distinguish between ions?

Although critical in biology, telling potassium from sodium is harder than you think!        Show more detail...

Biologically inspired membranes for the efficient desalination of water

Reducing the cost of seawater desalination by copying the action of cell membranes        Show more detail...

Watching proteins as they change shape

Monitoring the conformational changes of proteins        Show more detail...

Processes of community assembly

Developing bioinformatic tools for understanding the dynamics of : speciation, colonization, extinction and invasion within species assemblages        Show more detail...

Origins of a biodiversity hotspot flora

A phylogenetic analysis of the diversification of the Australian Proteaceae        Show more detail...

Evolvability

Exploring the causes, consequences and practical applications of evolvability        Show more detail...

Climate change and leaf eating mammals

Many wild herbivores show seasonal preferences for different plants or plant parts.        Show more detail...

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